HitPredict

Interactor 1: AKT1 (P31750)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (AKT1 kinase) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha) (Thymoma viral proto-oncogene)
Gene: AKT1

Interactor 2: ARRB2 (Q91YI4)
Beta-arrestin-2 (Arrestin beta-2)
Gene: ARRB2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

The method score is based on:

Property	Details
Experiments	19122674, 16051150
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0010628 - positive regulation of gene expression GO:0016567 - protein ubiquitination and 6 others more... GO:0031397 - negative regulation of protein ubiquitination GO:0033138 - positive regulation of peptidyl-serine phosphorylation GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:0071889 - 14-3-3 protein binding GO:0090201 - negative regulation of release of cytochrome c from mitochondria GO:0098978 - glutamatergic synapse
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	480
Mm

1	410

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024