HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: PPARG (P37231)
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) (Nuclear receptor subfamily 1 group C member 3)
Gene: PPARG

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26260846
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction GO:0019899 - enzyme binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 505
+	Hs
		740490 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		PPARG_HUMAN (1-505): 2.47e-165: 479: 100.00
+	Hs
		369315 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28
+	Hs
		369070 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28
+	Hs
		369354 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28
+	Dm
		709148 1433E_DROME (3-245): 4.63e-144: 405: 64.90		ECR_DROME (108-501): 2.18e-101: 325: 25.82
+	Mm
		509305 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		RARA_MOUSE (45-503): 3.03e-102: 316: 25.22
+	Hs
		909878 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70
+	Mm
		509343 1433B_MOUSE (1-246): 5.56e-141: 396: 98.78		RARA_MOUSE (45-503): 3.03e-102: 316: 25.22
+	Hs
		683595 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70
+	Hs
		369023 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28
+	Hs
		927369 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70
+	Hs
		320172 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		ERR2_HUMAN (25-502): 1.06e-104: 321: 19.14
+	Hs
		647162 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70
+	Hs
		369308 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28
+	Hs
		369071 1433S_HUMAN (3-239): 3.38e-100: 293: 68.62		ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28
+	Mm
		509296 1433G_MOUSE (3-246): 1.91e-109: 317: 75.40		RARA_MOUSE (45-503): 3.03e-102: 316: 25.22
+	Hs
		377266 1433F_HUMAN (4-244): 2.7e-107: 311: 75.51		GCR_HUMAN (18-503): 1.99e-98: 315: 17.85
+	Hs
		904942 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70
+	Hs
		377131 1433S_HUMAN (3-239): 3.38e-100: 293: 68.62		GCR_HUMAN (18-503): 1.99e-98: 315: 17.85
+	Hs
		684247 1433S_HUMAN (3-239): 3.38e-100: 293: 68.62		ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70