HitPredict

Interactor 1: IKBA (P25963)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)
Gene: NFKBIA

Interactor 2: UB2R1 (P49427)
Ubiquitin-conjugating enzyme E2 R1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme R1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme R1) (Ubiquitin-conjugating enzyme E2-32 kDa complementing) (Ubiquitin-conjugating enzyme E2-CDC34) (Ubiquitin-protein ligase R1)
Gene: CDC34

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	20347421
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 236
+	Hs
		683411 IKBA_HUMAN (1-317): 6.84e-85: 259: 100.00		UB2D1_HUMAN (9-167): 6.22e-71: 215: 34.38
+	Hs
		683429 IKBA_HUMAN (1-317): 6.84e-85: 259: 100.00		UB2D2_HUMAN (9-167): 6.29e-71: 215: 30.00
+	Hs
		683420 IKBA_HUMAN (1-317): 6.84e-85: 259: 100.00		UB2D3_HUMAN (9-167): 8.84e-70: 212: 29.38
+	Hs
		1295603 MIB1_HUMAN (1-299): 5.01e-70: 236: 25.53		UB2D4_HUMAN (9-167): 7.3e-72: 217: 32.50
+	Hs
		906699 MIB1_HUMAN (1-299): 5.01e-70: 236: 25.53		UB2D1_HUMAN (9-167): 6.22e-71: 215: 34.38
+	Hs
		982235 MIB1_HUMAN (1-299): 5.01e-70: 236: 25.53		UB2D2_HUMAN (9-167): 6.29e-71: 215: 30.00
+	Hs
		957128 MIB1_HUMAN (1-299): 5.01e-70: 236: 25.53		UB2D3_HUMAN (9-167): 8.84e-70: 212: 29.38
+	Hs
		626159 NFKB1_HUMAN (31-196): 3.49e-20: 93.1: 23.35		UB2D2_HUMAN (9-167): 6.29e-71: 215: 30.00
+	Hs
		626144 NFKB1_HUMAN (31-196): 3.49e-20: 93.1: 23.35		UB2D3_HUMAN (9-167): 8.84e-70: 212: 29.38
+	Hs
		884397 Q9H4D1_HUMAN (136-316): 3.11e-32: 128: 24.31		UBE2A_HUMAN (9-157): 1.04e-26: 102: 38.26