HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: M3K5 (Q99683)
Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5)
Gene: MAP3K5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 0.60 0.657

The method score is based on:

Property Details
Experiments 35271311, 21771788, 15023544
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019904 - protein domain specific binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 246
Hs

1 1374
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Dm
+ Hs
+ Hs
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024