HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: E41L1 (Q9H4G0)
Band 4.1-like protein 1 (Erythrocyte membrane protein band 4.1-like 1) (Neuronal protein 4.1) (4.1N)
Gene: EPB41L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33961781, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 881
+	Hs
		910025 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		E41L1_HUMAN (1-881): 0: 718: 100.00
+	Hs
		927524 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		E41L1_HUMAN (1-881): 0: 718: 100.00
+	Hs
		204644 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		E41L2_HUMAN (3-875): 0: 561: 42.93
+	Hs
		204620 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		E41L2_HUMAN (3-875): 0: 561: 42.93
+	Hs
		204648 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		E41L2_HUMAN (3-875): 0: 561: 42.93
+	Hs
		204614 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		E41L2_HUMAN (3-875): 0: 561: 42.93
+	Hs
		663970 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PTN4_HUMAN (69-722): 5.38e-160: 493: 29.29
+	Hs
		663962 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PTN4_HUMAN (69-722): 5.38e-160: 493: 29.29
+	Hs
		663973 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		PTN4_HUMAN (69-722): 5.38e-160: 493: 29.29
+	Hs
		683735 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		E41L5_HUMAN (60-763): 1.14e-151: 465: 25.89
+	Hs
		640229 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PTN3_HUMAN (69-717): 3e-138: 436: 24.14
+	Hs
		640216 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PTN3_HUMAN (69-717): 3e-138: 436: 24.14
+	Hs
		640230 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		PTN3_HUMAN (69-717): 3e-138: 436: 24.14
+	Hs
		927698 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		TLN1_HUMAN (42-879): 3.41e-119: 401: 10.75
+	Hs
		683499 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		FRMD5_HUMAN (95-568): 2.01e-126: 394: 31.21
+	Hs
		547003 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		EZRI_HUMAN (94-672): 1.1e-123: 387: 22.83
+	Hs
		910185 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		E41L3_HUMAN (458-875): 1.5e-50: 195: 29.79
+	Hs
		683836 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		E41L3_HUMAN (458-875): 1.5e-50: 195: 29.79
+	Hs
		927682 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		E41L3_HUMAN (458-875): 1.5e-50: 195: 29.79
+	Hs
		505612 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		EPB41_HUMAN (528-872): 1.64e-35: 147: 21.88