HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: NAV1 (Q8NEY1)
Neuron navigator 1 (Pore membrane and/or filament-interacting-like protein 3) (Steerin-1) (Unc-53 homolog 1) (unc53H1)
Gene: NAV1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 1877
+	Hs
		909831 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		NAV1_HUMAN (1-1877): 0: 748: 100.00
+	Mm
		910306 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		NAV1_MOUSE (1-1877): 0: 737: 95.96
+	Hs
		927321 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		NAV1_HUMAN (1-1877): 0: 748: 100.00
+	Hs
		684186 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		NAV2_HUMAN (57-1877): 2.29e-150: 518: 33.13
+	Hs
		909778 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		NAV2_HUMAN (57-1877): 2.29e-150: 518: 33.13
+	Hs
		927269 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		NAV2_HUMAN (57-1877): 2.29e-150: 518: 33.13
+	Hs
		909455 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ANK2_HUMAN (6-1441): 2.24e-38: 160: 10.78
+	Hs
		926936 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		ANK2_HUMAN (6-1441): 2.24e-38: 160: 10.78
+	Hs
		684401 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SRRM2_HUMAN (486-1510): 5.71e-15: 83.5: 9.90
+	Hs
		927549 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		TENS1_HUMAN (114-1428): 1.23e-27: 125: 12.85
+	Hs
		909712 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		OTOG_HUMAN (34-576): 3.3e-18: 94.2: 9.72
+	Hs
		297821 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		K0754_HUMAN (26-425): 9.52e-18: 92.7: 12.29
+	Hs
		910167 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		SRRM2_HUMAN (486-1510): 5.71e-15: 83.5: 9.90
+	Hs
		927196 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		OTOG_HUMAN (34-576): 3.3e-18: 94.2: 9.72
+	Hs
		297824 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		K0754_HUMAN (26-425): 9.52e-18: 92.7: 12.29
+	Hs
		927045 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MDC1_HUMAN (453-1439): 1.16e-17: 92.3: 10.02
+	Hs
		646808 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		ANK2_HUMAN (6-1441): 2.24e-38: 160: 10.78
+	Hs
		927666 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		SRRM2_HUMAN (486-1510): 5.71e-15: 83.5: 9.90
+	Hs
		927352 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		TITIN_HUMAN (49-1203): 1.21e-11: 72.7: 9.26
+	Hs
		647025 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		OTOG_HUMAN (34-576): 3.3e-18: 94.2: 9.72