HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: SH3B4 (Q9P0V3)
SH3 domain-binding protein 4 (EH-binding protein 10) (Transferrin receptor-trafficking protein)
Gene: SH3BP4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	15778465, 33761321
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 963
+	Hs
		910108 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Mm
		250874 1433S_MOUSE (1-248): 4.84e-154: 429: 97.58		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Mm
		910324 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Hs
		927602 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Mm
		926863 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Hs
		647337 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Hs
		683771 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Hs
		905197 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Mm
		933138 1433T_MOUSE (1-238): 7.63e-107: 310: 71.43		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Hs
		982565 1433F_HUMAN (2-242): 2.78e-96: 283: 64.20		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Mm
		1265696 1433B_MOUSE (1-239): 3.73e-99: 290: 68.62		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Mm
		905357 1433G_MOUSE (1-242): 1.86e-98: 289: 65.16		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Mm
		935606 1433F_MOUSE (2-242): 1.72e-96: 284: 64.20		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Hs
		909710 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MACC1_HUMAN (140-958): 0: 1340: 43.71