HitPredict

Interactor 1: STIP1 (P31948)
Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)
Gene: STIP1

Interactor 2: H90B2 (Q58FF8)
Putative heat shock protein HSP 90-beta 2 (Heat shock protein 90-beta b) (Heat shock protein 90Bb)
Gene: HSP90AB2P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	HSP90~TPR_8
Common GO terms	GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 381
+	Hs
		684788 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		H90B3_HUMAN (1-381): 8.64e-116: 350: 59.04
+	Hs
		1123473 DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28		H90B2_HUMAN (1-381): 2.81e-170: 482: 100.00
+	Hs
		684791 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		HS904_HUMAN (57-381): 4.72e-80: 253: 37.27
+	Hs
		684849 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		Q86SX1_HUMAN (1-136): 5.94e-78: 242: 68.79
+	Hs
		538123 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		ENPL_HUMAN (185-381): 1.31e-65: 224: 34.98
+	At
		878278 HSOP2_ARATH (3-543): 4.73e-97: 307: 41.86		HS902_ARATH (183-381): 3.49e-67: 226: 45.59
+	Hs
		684790 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		HS905_HUMAN (108-355): 1.06e-55: 187: 60.08
+	Hs
		684674 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		TRAP1_HUMAN (135-380): 3.01e-42: 158: 20.45
+	Hs
		684787 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		H90B4_HUMAN (109-247): 1.76e-32: 129: 75.54
+	Hs
		437930 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41
+	Hs
		111934 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		K9JA46_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Hs
		431574 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Dm
		365481 Q9VPN5_DROME (1-542): 1.4e-79: 259: 47.42		HSP83_DROME (109-251): 7.34e-26: 111: 63.64
+	Hs
		538353 SGTB_HUMAN (213-348): 5.73e-32: 126: 31.39		ENPL_HUMAN (185-381): 1.31e-65: 224: 34.98
+	Hs
		438464 DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41
+	Hs
		432195 DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Hs
		438533 RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41
+	Hs
		432268 RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Sc
		366262 TOM71_YEAST (71-537): 1.63e-23: 106: 12.25		HSP82_YEAST (110-246): 4.66e-20: 94: 50.37
+	Sc
		543696 TOM71_YEAST (71-537): 1.63e-23: 106: 12.25		HSC82_YEAST (110-246): 4.47e-19: 90.9: 50.37