Interactor 1: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Interactor 2: U2AF1 (Q01081)
Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 small nuclear RNA auxiliary factor 1) (U2 snRNP auxiliary factor small subunit)
Gene: U2AF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 21516116, 26641092, 32296183, 26264872, 35271311, 31839598, 22365833, 25416956, 16189514, 28514442, 1388271, 33961781, 21988832, 8647433, unassigned1304, 21460037, 11551507
Identification Methods two hybrid, affinity chromatography technology, cross-linking study, pull down, genetic interference, validated two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach, two hybrid prey pooling approach, x-ray crystallography and 2 others

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Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RRM_1~RRM_1, RRM_1~zf-CCCH
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex
GO:0006397 - mRNA processing
and 3 others

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Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 475
Hs

1 240
+ Hs
+ Hs
+ At
+ Dm
+ Dm
+ Sp
+ Ce
+ Hs
+ Hs
+ Pf

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Last updated: 11Aug2025