Interactor 1: PRDX2 (P32119)
Peroxiredoxin-2 (EC 1.11.1.24) (Natural killer cell-enhancing factor B) (NKEF-B) (PRP) (Thiol-specific antioxidant protein) (TSA) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Thioredoxin-dependent peroxiredoxin 2)
Gene: PRDX2

Interactor 2: PRDX4 (Q13162)
Peroxiredoxin-4 (EC 1.11.1.24) (Antioxidant enzyme AOE372) (AOE37-2) (Peroxiredoxin IV) (Prx-IV) (Thioredoxin peroxidase AO372) (Thioredoxin-dependent peroxide reductase A0372) (Thioredoxin-dependent peroxiredoxin 4)
Gene: PRDX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 21988832
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains 1-cysPrx_C~1-cysPrx_C, 1-cysPrx_C~AhpC-TSA, AhpC-TSA~AhpC-TSA
Common GO terms GO:0005829 - cytosol
GO:0006979 - response to oxidative stress
GO:0008379 - thioredoxin peroxidase activity
GO:0042744 - hydrogen peroxide catabolic process
GO:0045454 - cell redox homeostasis
and 1 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 198
Hs

1 271
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Bt
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Sp
+ Ss
+ Sc

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Last updated: 15 Jul 2024