HitPredict

Interactor 1: PRDX2 (P32119)
Peroxiredoxin-2 (EC 1.11.1.24) (Natural killer cell-enhancing factor B) (NKEF-B) (PRP) (Thiol-specific antioxidant protein) (TSA) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Thioredoxin-dependent peroxiredoxin 2)
Gene: PRDX2

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31046837
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006979 - response to oxidative stress GO:0034599 - cellular response to oxidative stress GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 198 Hs			1 2527
+	Hs
		1130800 V9HW12_HUMAN (1-198): 3.46e-104: 299: 100.00		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		670963 PRDX3_HUMAN (2-198): 8.33e-101: 293: 63.45		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		989314 PRDX1_HUMAN (1-197): 7.49e-100: 288: 77.78		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1026699 PRDX4_HUMAN (5-198): 2.62e-96: 282: 70.10		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130809 V9HW63_HUMAN (5-198): 2.62e-96: 282: 70.10		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130816 V9HWC7_HUMAN (4-196): 1.88e-67: 207: 29.13		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		201232 PRDX3_HUMAN (2-198): 8.33e-101: 293: 63.45		M3K7_HUMAN (1869-2132): 8.36e-23: 107: 28.83
+	Hs
		201231 PRDX6_HUMAN (4-196): 1.88e-67: 207: 29.13		M3K7_HUMAN (1869-2132): 8.36e-23: 107: 28.83