HitPredict

Interactor 1: HNRDL (O14979)
Heterogeneous nuclear ribonucleoprotein D-like (hnRNP D-like) (hnRNP DL) (AU-rich element RNA-binding factor) (JKT41-binding protein) (Protein laAUF1)
Gene: HNRNPDL

Interactor 2: ELAV1 (Q15717)
ELAV-like protein 1 (Hu-antigen R) (HuR)
Gene: ELAVL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 420 Hs			1 326
+	Hs
		485100 ROA1_HUMAN (136-317): 5.4e-82: 258: 36.17		ELAV2_HUMAN (3-326): 1.34e-88: 271: 70.62
+	Hs
		485166 ROA1_HUMAN (136-317): 5.4e-82: 258: 36.17		ELAV1_HUMAN (1-326): 6.43e-89: 271: 100.00
+	Hs
		909586 ROA3_HUMAN (140-317): 8.73e-82: 257: 37.50		ELAV1_HUMAN (1-326): 6.43e-89: 271: 100.00
+	Hs
		650726 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		ELAV2_HUMAN (3-326): 1.34e-88: 271: 70.62
+	Hs
		650777 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		ELAV1_HUMAN (1-326): 6.43e-89: 271: 100.00
+	Hs
		650756 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		ELAV3_HUMAN (1-326): 1.13e-83: 258: 55.04
+	Hs
		1120167 HNRPD_HUMAN (111-420): 2.87e-63: 209: 56.45		ELAV1_HUMAN (1-326): 6.43e-89: 271: 100.00
+	Hs
		1090216 PABP4_HUMAN (58-335): 1.03e-59: 207: 19.05		ELAV2_HUMAN (3-326): 1.34e-88: 271: 70.62
+	Hs
		1101971 PABP4_HUMAN (58-335): 1.03e-59: 207: 19.05		ELAV1_HUMAN (1-326): 6.43e-89: 271: 100.00
+	Dm
		620691 RB27C_DROME (143-407): 8.53e-78: 248: 29.49		SXL_DROME (1-199): 2.38e-54: 182: 43.72
+	Hs
		172001 HNRDL_HUMAN (1-420): 2.03e-91: 284: 100.00		PABP1_HUMAN (234-325): 6.64e-19: 89.3: 19.57
+	Hs
		172092 HNRDL_HUMAN (1-420): 2.03e-91: 284: 100.00		PABP4_HUMAN (234-325): 1.05e-18: 88.5: 20.65
+	Dm
		636386 RB27C_DROME (143-407): 8.53e-78: 248: 29.49		PABP_DROME (18-326): 1.59e-22: 100: 25.24
+	Hs
		484876 ROA1_HUMAN (136-317): 5.4e-82: 258: 36.17		PABP1_HUMAN (234-325): 6.64e-19: 89.3: 19.57
+	Hs
		485114 ROA1_HUMAN (136-317): 5.4e-82: 258: 36.17		PABP4_HUMAN (234-325): 1.05e-18: 88.5: 20.65
+	Hs
		550189 ROA3_HUMAN (140-317): 8.73e-82: 257: 37.50		PABP1_HUMAN (234-325): 6.64e-19: 89.3: 19.57
+	Hs
		550120 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		PABP1_HUMAN (234-325): 6.64e-19: 89.3: 19.57
+	Hs
		550278 HNRPD_HUMAN (111-420): 2.87e-63: 209: 56.45		PABP1_HUMAN (234-325): 6.64e-19: 89.3: 19.57
+	Hs
		550262 PABP4_HUMAN (58-335): 1.03e-59: 207: 19.05		PABP1_HUMAN (234-325): 6.64e-19: 89.3: 19.57
+	Hs
		506129 PABP4_HUMAN (58-335): 1.03e-59: 207: 19.05		PAB4L_HUMAN (20-184): 3.04e-12: 68.6: 28.42