HitPredict

Interactor 1: ARRB2 (P32121)
Beta-arrestin-2 (Arrestin beta-2) (Non-visual arrestin-3)
Gene: ARRB2

Interactor 2: MK10 (P53779)
Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)
Gene: MAPK10

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	11356842, 19782076
Identification Methods	affinity chromatography technology, unspecified method, peptide array
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 409 Hs			1 464
+	Rn
		663950 ARRB2_RAT (1-409): 0: 682: 95.85		MK10_RAT (1-464): 0: 516: 99.14
+	Hs
		827134 ARRB1_HUMAN (1-407): 0: 661: 76.15		MK10_HUMAN (1-464): 0: 517: 100.00
+	Hs
		685833 ARRB2_HUMAN (1-409): 0: 688: 100.00		MK09_HUMAN (39-464): 1.45e-163: 469: 83.80
+	Hs
		800859 ARRB1_HUMAN (1-407): 0: 661: 76.15		MK09_HUMAN (39-464): 1.45e-163: 469: 83.80
+	Hs
		827213 ARRB1_HUMAN (1-407): 0: 661: 76.15		MK14_HUMAN (42-408): 2.57e-133: 390: 45.95
+	Hs
		647481 ARRB2_HUMAN (1-409): 0: 688: 100.00		MK03_HUMAN (58-397): 1.2e-84: 266: 42.12
+	Hs
		658808 ARRB2_HUMAN (1-409): 0: 688: 100.00		MK01_HUMAN (58-397): 8.71e-85: 266: 42.98
+	Hs
		647514 ARRB1_HUMAN (1-407): 0: 661: 76.15		MK03_HUMAN (58-397): 1.2e-84: 266: 42.12
+	Hs
		658850 ARRB1_HUMAN (1-407): 0: 661: 76.15		MK01_HUMAN (58-397): 8.71e-85: 266: 42.98