HitPredict

Interactor 1: P5CR (P32263)
Pyrroline-5-carboxylate reductase (P5C reductase) (P5CR) (EC 1.5.1.2)
Gene: PRO3

Interactor 2: P5CR (P32263)
Pyrroline-5-carboxylate reductase (P5C reductase) (P5CR) (EC 1.5.1.2)
Gene: PRO3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.856

The method score is based on:

Property Details
Experiments 10688190, 18467557, 18719252
Identification Methods two hybrid, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains F420_oxidored~F420_oxidored, F420_oxidored~P5CR_dimer, P5CR_dimer~P5CR_dimer
Common GO terms GO:0004735 - pyrroline-5-carboxylate reductase activity
GO:0005737 - cytoplasm
GO:0006561 - proline biosynthetic process
GO:0055129 - L-proline biosynthetic process
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 286
Sc

1 286
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+ Mm
+ Ce
+ Dm
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+ Hp
+ Cj

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Last updated: 15 Jul 2024