HitPredict

Interactor 1: PTBP1 (P26599)
Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I)
Gene: PTBP1

Interactor 2: DAZL (Q92904)
Deleted in azoospermia-like (DAZ homolog) (DAZ-like autosomal) (Deleted in azoospermia-like 1) (SPGY-like-autosomal)
Gene: DAZL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~RRM_5
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 557 Hs			1 295
+	Hs
		344271 PTBP3_HUMAN (1-557): 5.42e-102: 320: 74.01		DAZL_HUMAN (1-295): 8.93e-75: 232: 100.00
+	Hs
		650603 PTBP1_HUMAN (1-557): 1.59e-121: 370: 100.00		ROA2_HUMAN (36-125): 1.61e-23: 100: 18.48
+	Hs
		1332291 HNRLL_HUMAN (44-556): 1.25e-96: 306: 25.91		BOLL_HUMAN (30-267): 6.35e-39: 139: 29.20
+	Hs
		550395 PABP1_HUMAN (3-375): 2.22e-45: 171: 13.58		DAZL_HUMAN (1-295): 8.93e-75: 232: 100.00
+	Hs
		1102045 PABP4_HUMAN (3-378): 2.7e-44: 168: 10.62		DAZL_HUMAN (1-295): 8.93e-75: 232: 100.00
+	Hs
		344105 PTBP3_HUMAN (1-557): 5.42e-102: 320: 74.01		TIA1_HUMAN (35-126): 1.42e-13: 72.1: 23.40
+	Hs
		344099 PTBP3_HUMAN (1-557): 5.42e-102: 320: 74.01		RBMS1_HUMAN (40-125): 3.41e-09: 59.1: 22.99
+	Hs
		550120 PABP1_HUMAN (3-375): 2.22e-45: 171: 13.58		ROA2_HUMAN (36-125): 1.61e-23: 100: 18.48
+	Hs
		550262 PABP1_HUMAN (3-375): 2.22e-45: 171: 13.58		PABP4_HUMAN (34-122): 6.18e-17: 82.9: 19.57
+	Hs
		550311 PABP1_HUMAN (3-375): 2.22e-45: 171: 13.58		PAP1L_HUMAN (32-122): 5.22e-17: 82.9: 15.96
+	Hs
		1102095 PABP3_HUMAN (3-375): 6.42e-45: 170: 13.42		PABP4_HUMAN (34-122): 6.18e-17: 82.9: 19.57
+	Hs
		1197178 PABP3_HUMAN (3-375): 6.42e-45: 170: 13.42		PAP1L_HUMAN (32-122): 5.22e-17: 82.9: 15.96
+	Hs
		550097 PABP1_HUMAN (3-375): 2.22e-45: 171: 13.58		PABP1_HUMAN (32-126): 1.03e-15: 79: 18.37
+	Hs
		550464 PABP1_HUMAN (3-375): 2.22e-45: 171: 13.58		PABP3_HUMAN (32-122): 1.11e-14: 75.9: 18.09
+	Hs
		550137 PABP1_HUMAN (3-375): 2.22e-45: 171: 13.58		TIA1_HUMAN (35-126): 1.42e-13: 72.1: 23.40
+	Mm
		710979 PABP1_MOUSE (3-375): 1.95e-45: 171: 13.58		TIA1_MOUSE (35-126): 1.4e-13: 72.1: 23.40
+	Hs
		550134 PABP1_HUMAN (3-375): 2.22e-45: 171: 13.58		RBMS1_HUMAN (40-125): 3.41e-09: 59.1: 22.99
+	Hs
		713771 PABP4_HUMAN (3-378): 2.7e-44: 168: 10.62		RBMS1_HUMAN (40-125): 3.41e-09: 59.1: 22.99