HitPredict

Interactor 1: BTAF1 (P32333)
TATA-binding protein-associated factor MOT1 (TBP-associated factor MOT1) (EC 3.6.4.-) (Modifier of transcription 1)
Gene: MOT1

Interactor 2: NCB2 (Q92317)
Negative cofactor 2 complex subunit beta (NC2 complex subunit beta) (Transcriptional repressor YDR1)
Gene: NCB2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.672

Property	Details
Experiments	18703679, 18596064, 37968396, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0017025 - TBP-class protein binding GO:0045898 - regulation of RNA polymerase II transcription preinitiation complex assembly
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1867 Sc			1 146
+	Sc
		687746 BTAF1_YEAST (1-1867): 0: 2157: 100.00		DPB4_YEAST (6-103): 2.73e-22: 89.3: 18.81
+	Hs
		658740 SMCA1_HUMAN (1166-1843): 0: 605: 26.83		DPOE3_HUMAN (1-119): 2.81e-35: 120: 27.73
+	Hs
		229503 SMCA5_HUMAN (1154-1862): 0: 603: 26.69		DPOE3_HUMAN (1-119): 2.81e-35: 120: 27.73
+	Dm
		1097632 ISWI_DROME (1161-1843): 0: 587: 27.26		DPOE3_DROME (1-113): 1.76e-27: 100: 25.66
+	Sc
		979818 ISW2_YEAST (1159-1853): 0: 589: 27.42		DPB4_YEAST (6-103): 2.73e-22: 89.3: 18.81
+	Sc
		696252 STH1_YEAST (1240-1781): 8.75e-76: 280: 35.28		DPB4_YEAST (6-103): 2.73e-22: 89.3: 18.81