HitPredict

Interactor 1: PP4C (P32345)
Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (EC 3.1.3.16) (Phosphatase PP2A-like catalytic subunit PPH3)
Gene: PPH3

Interactor 2: KSP1 (P38691)
Serine/threonine-protein kinase KSP1 (EC 2.7.11.1)
Gene: KSP1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	11805837
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 308 Sc			1 1029
+	Hs
		682162 PP2AA_HUMAN (3-308): 0: 518: 52.29		AKT2_HUMAN (42-418): 1.2e-127: 398: 16.41
+	Hs
		681777 PP2AA_HUMAN (3-308): 0: 518: 52.29		AKT1_HUMAN (44-411): 1.96e-126: 394: 16.75
+	Mm
		682104 PP2AA_MOUSE (3-308): 0: 518: 52.29		AKT1_MOUSE (44-411): 1.96e-126: 394: 16.75
+	Hs
		931045 PP2AA_HUMAN (3-308): 0: 518: 52.29		AKT3_HUMAN (3-421): 3.39e-126: 394: 15.08
+	Hs
		647866 PP2AB_HUMAN (3-308): 0: 518: 52.29		MARK3_HUMAN (41-657): 3.02e-121: 390: 16.72
+	Hs
		681698 PP1G_HUMAN (2-301): 0: 509: 41.42		AKT1_HUMAN (44-411): 1.96e-126: 394: 16.75
+	Mm
		682103 PP1A_MOUSE (2-290): 0: 508: 43.96		AKT1_MOUSE (44-411): 1.96e-126: 394: 16.75
+	Hs
		681767 PP1A_HUMAN (2-290): 0: 507: 43.62		AKT1_HUMAN (44-411): 1.96e-126: 394: 16.75
+	Hs
		915261 PP2AB_HUMAN (3-308): 0: 518: 52.29		MARK4_HUMAN (50-648): 9.43e-119: 383: 15.07
+	Hs
		930826 PP2AA_HUMAN (3-308): 0: 518: 52.29		AAPK1_HUMAN (64-609): 9.19e-121: 382: 15.51
+	Hs
		116996 PP2AA_HUMAN (3-308): 0: 518: 52.29		SGK1_HUMAN (2-396): 1.03e-121: 381: 16.10
+	Rn
		871244 PP2AA_RAT (3-308): 0: 518: 52.29		AAPK1_RAT (64-609): 1.12e-119: 380: 15.33
+	Rn
		871210 PP1A_RAT (2-290): 0: 507: 43.62		AAPK1_RAT (64-609): 1.12e-119: 380: 15.33
+	Sc
		419801 PP11_YEAST (5-286): 2.24e-130: 375: 58.10		SNF1_YEAST (66-518): 6.63e-101: 332: 16.09
+	Mm
		1141534 PPP6_MOUSE (2-308): 5.74e-139: 396: 59.28		RIPK1_MOUSE (78-458): 3.87e-83: 285: 21.83
+	Hs
		135411 PPP6_HUMAN (2-308): 1.95e-138: 395: 59.28		AAPK2_HUMAN (75-377): 8.35e-77: 264: 22.36
+	Ce
		108336 PP2A_CAEEL (1-308): 0: 520: 53.25		UNC51_CAEEL (143-307): 1.88e-16: 86.7: 34.24
+	Hs
		930841 PP2AA_HUMAN (3-308): 0: 518: 52.29		KCC1A_HUMAN (134-335): 2.46e-17: 87: 30.05
+	Hs
		262251 PP1A_HUMAN (2-290): 0: 507: 43.62		ULK1_HUMAN (143-301): 2.1e-16: 86.7: 33.53