Protein: TRIB2
Tribbles homolog 2 (TRB-2)

Gene: TRIB2
Organism: Homo sapiens
Interactions: 50
UniProt ID: Q92519

Gene Ontology (top 5):
GO:0004860 - protein kinase inhibitor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005856 - cytoskeleton
GO:0031434 - mitogen-activated protein kinase kinase binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

62998

POTEF
POTE ankyrin domain family member F

2

8

High-throughput

0.811

High

1363535

TRIB1
Tribbles homolog 1

2

17

High-throughput

0.811

High

1324356

STK40
Serine/threonine-protein kinase 40

3

18

High-throughput

0.779

High

1340764

COP1
E3 ubiquitin-protein ligase COP1

5

9

Small-scale

0.718

High

854195

KI67
Proliferation marker protein Ki-67

1

2

High-throughput

0.691

High

1121711

SAFB2
Scaffold attachment factor B2

1

7

High-throughput

0.691

High

1363534

RBM14
RNA-binding protein 14

1

6

High-throughput

0.691

High

1363545

RALY
RNA-binding protein Raly

1

4

High-throughput

0.691

High

1272650

DET1
DET1 homolog

3

2

High-throughput

0.675

High

1363546

FBW1A
F-box/WD repeat-containing protein 1A

3

6

Small-scale

0.674

High

1363543

UBQL4
Ubiquilin-4

1

7

High-throughput

0.656

High

1209455

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

9

High-throughput

0.647

High

532818

CH60
60 kDa heat shock protein, mitochondrial

2

8

High-throughput

0.628

High

909361

UB2E1
Ubiquitin-conjugating enzyme E2 E1

2

5

High-throughput

0.628

High

1213009

SKT
Sickle tail protein homolog

2

1

High-throughput

0.628

High

1363537

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

2

2

High-throughput

0.628

High

1363542

SLAF7
SLAM family member 7

1

1

High-throughput

0.625

High

1363541

SMUF1
E3 ubiquitin-protein ligase SMURF1

2

17

Small-scale

0.624

High

171294

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

3

Small-scale

0.618

High

658616

KS6B1
Ribosomal protein S6 kinase beta-1

1

15

Small-scale

0.618

High

1363539

PARVG
Gamma-parvin

2

5

High-throughput

0.606

High

1032025

TFAP4
Transcription factor AP-4

2

0

High-throughput

0.602

High

182405

GSTA4
Glutathione S-transferase A4

2

3

High-throughput

0.574

High

1194645

KCD21
BTB/POZ domain-containing protein KCTD21

2

6

High-throughput

0.574

High

277758

H2AY
Core histone macro-H2A.1

1

3

High-throughput

0.536

High

601787

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.536

High

1010336

BASP1
Brain acid soluble protein 1

1

4

High-throughput

0.536

High

1322604

RPTOR
Regulatory-associated protein of mTOR

1

10

High-throughput

0.536

High

1336256

LS14A
Protein LSM14 homolog A

1

1

High-throughput

0.536

High

1363538

DHRS6
Dehydrogenase/reductase SDR family member 6

1

1

High-throughput

0.536

High

1363544

BCLF1
Bcl-2-associated transcription factor 1

1

3

High-throughput

0.536

High

1363547

TR150
Thyroid hormone receptor-associated protein 3

1

3

High-throughput

0.536

High

688085

EF1G
Elongation factor 1-gamma

1

5

High-throughput

0.515

High

542595

TOP2A
DNA topoisomerase 2-alpha

1

0

High-throughput

0.513

High

1363533

ANM6
Protein arginine N-methyltransferase 6

1

4

High-throughput

0.508

High

422747

A4
Amyloid-beta precursor protein

1

11

High-throughput

0.501

High

887062

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

Small-scale

0.501

High

1164491

MIC60
MICOS complex subunit MIC60

1

1

High-throughput

0.489

High

487586

PARP1
Poly [ADP-ribose] polymerase 1

1

7

Small-scale

0.479

High

535356

BIP
Endoplasmic reticulum chaperone BiP

1

8

Small-scale

0.479

High

623464

RO52
E3 ubiquitin-protein ligase TRIM21

1

2

Small-scale

0.479

High

1112628

CUL1
Cullin-1

1

7

Small-scale

0.479

High

1146954

PCBP2
Poly(rC)-binding protein 2

1

6

Small-scale

0.479

High

1363536

S10AD
Protein S100-A13

1

5

High-throughput

0.479

High

1279673

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

4

High-throughput

0.470

High

1363540

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

0

Small-scale

0.458

High

1094223

ACACA
Acetyl-CoA carboxylase 1

1

8

Small-scale

0.457

High

1328374

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.279

Low

1363548

CHTOP
Chromatin target of PRMT1 protein

1

0

High-throughput

0.279

Low

1204252

CAR16
Caspase recruitment domain-containing protein 16

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025