HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: BCAR1 (P56945)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene: BCAR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 870
+	Hs
		942531 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		BCAR1_HUMAN (1-870): 1.95e-107: 353: 100.00
+	Hs
		942542 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		BCAR1_HUMAN (1-870): 1.95e-107: 353: 100.00
+	Hs
		972132 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		MACF1_HUMAN (505-867): 2.95e-74: 268: 13.79
+	Hs
		691538 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		MACF1_HUMAN (505-867): 2.95e-74: 268: 13.79
+	Hs
		971426 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		DYST_HUMAN (457-866): 1.24e-66: 245: 12.07
+	Hs
		690925 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		DYST_HUMAN (457-866): 1.24e-66: 245: 12.07
+	Hs
		990123 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		DYST_HUMAN (457-866): 1.24e-66: 245: 12.07
+	Hs
		971672 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		DNMBP_HUMAN (7-561): 3.15e-28: 125: 14.87
+	Hs
		274129 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		ANR17_HUMAN (69-494): 5.56e-27: 121: 14.82
+	Hs
		990140 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		ACK1_HUMAN (9-499): 5.89e-30: 130: 15.35
+	Hs
		319058 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		K0754_HUMAN (125-664): 3.53e-26: 118: 12.38
+	Hs
		691151 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		DNMBP_HUMAN (7-561): 3.15e-28: 125: 14.87
+	Hs
		990380 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		DNMBP_HUMAN (7-561): 3.15e-28: 125: 14.87
+	Hs
		274099 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		ANR17_HUMAN (69-494): 5.56e-27: 121: 14.82
+	Hs
		274131 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		ANR17_HUMAN (69-494): 5.56e-27: 121: 14.82
+	Hs
		319061 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		K0754_HUMAN (125-664): 3.53e-26: 118: 12.38
+	Hs
		990225 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		MDC1_HUMAN (56-759): 1.44e-20: 100: 8.77
+	Hs
		971678 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		OTOG_HUMAN (274-769): 1.39e-17: 90.4: 10.85
+	Hs
		691153 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		OTOG_HUMAN (274-769): 1.39e-17: 90.4: 10.85
+	Hs
		691291 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		TITIN_HUMAN (56-404): 7.29e-09: 62.1: 14.93