HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: TET2 (Q6N021)
Methylcytosine dioxygenase TET2 (EC 1.14.11.80)
Gene: TET2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	29735542, 36931259, 23353889
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 2002
+	Hs
		971647 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		990357 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		729947 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		730676 1433S_HUMAN (1-236): 9.9e-108: 312: 71.85		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		1049424 1433F_HUMAN (2-242): 7.19e-106: 307: 71.43		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		966471 1433G_HUMAN (1-242): 5.51e-105: 305: 70.33		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		971800 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		TET1_HUMAN (1844-2002): 1.37e-56: 220: 49.06
+	Hs
		691263 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		TET1_HUMAN (1844-2002): 1.37e-56: 220: 49.06
+	Hs
		1049583 1433F_HUMAN (2-242): 7.19e-106: 307: 71.43		TET1_HUMAN (1844-2002): 1.37e-56: 220: 49.06
+	Hs
		966643 1433G_HUMAN (1-242): 5.51e-105: 305: 70.33		TET1_HUMAN (1844-2002): 1.37e-56: 220: 49.06