HitPredict

Interactor 1: MKK1 (P32490)
MAP kinase kinase MKK1/SSP32 (EC 2.7.12.2)
Gene: MKK1

Interactor 2: NST1 (P53935)
Stress response protein NST1 (Negatively-affecting salt tolerance protein 1)
Gene: NST1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	26787465
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 508 Sc			1 1240
+	Sc
		691236 MKK2_YEAST (1-507): 1.25e-126: 380: 55.60		NST1_YEAST (1-1240): 0: 657: 100.00
+	Hs
		625177 CDK2_HUMAN (218-499): 1.01e-123: 365: 20.86		MYH10_HUMAN (26-925): 6.28e-49: 193: 10.18
+	Hs
		568568 KAPCA_HUMAN (184-501): 4.11e-121: 360: 22.22		MYH10_HUMAN (26-925): 6.28e-49: 193: 10.18
+	Hs
		681696 AKT1_HUMAN (118-501): 1.59e-121: 366: 19.45		MYH9_HUMAN (213-964): 1.38e-33: 143: 10.30
+	Hs
		724784 KPCE_HUMAN (82-501): 3.47e-118: 366: 21.89		MYH9_HUMAN (213-964): 1.38e-33: 143: 10.30
+	Hs
		625176 CDK2_HUMAN (218-499): 1.01e-123: 365: 20.86		MYH9_HUMAN (213-964): 1.38e-33: 143: 10.30
+	Hs
		568567 KAPCA_HUMAN (184-501): 4.11e-121: 360: 22.22		MYH9_HUMAN (213-964): 1.38e-33: 143: 10.30
+	Hs
		528401 CDK2_HUMAN (218-499): 1.01e-123: 365: 20.86		MYH8_HUMAN (2-823): 6.38e-31: 134: 9.52
+	Hs
		522609 STK4_HUMAN (202-489): 9.92e-112: 341: 35.17		MYH7_HUMAN (2-752): 4.32e-31: 135: 11.43
+	Hs
		551616 AKT1_HUMAN (118-501): 1.59e-121: 366: 19.45		DESP_HUMAN (69-774): 5.03e-20: 99.3: 11.73
+	Hs
		551672 KPCE_HUMAN (82-501): 3.47e-118: 366: 21.89		DESP_HUMAN (69-774): 5.03e-20: 99.3: 11.73
+	Hs
		551610 CDK2_HUMAN (218-499): 1.01e-123: 365: 20.86		DESP_HUMAN (69-774): 5.03e-20: 99.3: 11.73
+	Hs
		160569 AURKA_HUMAN (90-500): 1.01e-122: 366: 24.03		NUMA1_HUMAN (5-560): 2.67e-11: 70.8: 8.45
+	Hs
		625446 CDK2_HUMAN (218-499): 1.01e-123: 365: 20.86		PLEC_HUMAN (3-628): 1.49e-11: 71.5: 10.67
+	Hs
		625440 CDK2_HUMAN (218-499): 1.01e-123: 365: 20.86		NUMA1_HUMAN (5-560): 2.67e-11: 70.8: 8.45
+	Hs
		522545 STK4_HUMAN (202-489): 9.92e-112: 341: 35.17		MYH1_HUMAN (370-938): 2.04e-17: 90.7: 10.46
+	Hs
		502911 STK4_HUMAN (202-489): 9.92e-112: 341: 35.17		MYH3_HUMAN (351-937): 4.02e-17: 89.9: 10.73
+	Hs
		625530 CDK2_HUMAN (218-499): 1.01e-123: 365: 20.86		MY18A_HUMAN (70-505): 2.02e-09: 64.6: 10.91
+	Hs
		1047932 KCC1A_HUMAN (212-507): 5.45e-119: 356: 25.89		NUMA1_HUMAN (5-560): 2.67e-11: 70.8: 8.45
+	Xl
		140374 AURAA_XENLA (77-502): 3.11e-121: 363: 22.95		INCEA_XENLA (579-836): 7.09e-09: 62.5: 20.69