HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: PRAG1 (Q86YV5)
Inactive tyrosine-protein kinase PRAG1 (PEAK1-related kinase-activating pseudokinase 1) (Pragmin) (Sugen kinase 223) (SgK223)
Gene: PRAG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	14-3-3~PK_Tyr_Ser-Thr
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 1406
+	Hs
		971742 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		PRAG1_HUMAN (1-1406): 0: 2304: 100.00
+	Hs
		730027 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		PRAG1_HUMAN (1-1406): 0: 2304: 100.00
+	Hs
		730741 1433S_HUMAN (1-236): 9.9e-108: 312: 71.85		PRAG1_HUMAN (1-1406): 0: 2304: 100.00
+	Hs
		1049520 1433F_HUMAN (2-242): 7.19e-106: 307: 71.43		PRAG1_HUMAN (1-1406): 0: 2304: 100.00
+	Hs
		966570 1433G_HUMAN (1-242): 5.51e-105: 305: 70.33		PRAG1_HUMAN (1-1406): 0: 2304: 100.00
+	Hs
		972004 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		PEAK1_HUMAN (14-104): 7.62e-10: 66: 40.43
+	Hs
		691437 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		PEAK1_HUMAN (14-104): 7.62e-10: 66: 40.43
+	Hs
		990741 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		PEAK1_HUMAN (14-104): 7.62e-10: 66: 40.43
+	Hs
		730246 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		PEAK1_HUMAN (14-104): 7.62e-10: 66: 40.43
+	Hs
		730891 1433S_HUMAN (1-236): 9.9e-108: 312: 71.85		PEAK1_HUMAN (14-104): 7.62e-10: 66: 40.43
+	Hs
		1049789 1433F_HUMAN (2-242): 7.19e-106: 307: 71.43		PEAK1_HUMAN (14-104): 7.62e-10: 66: 40.43
+	Hs
		966879 1433G_HUMAN (1-242): 5.51e-105: 305: 70.33		PEAK1_HUMAN (14-104): 7.62e-10: 66: 40.43