Protein: PRAG1
Inactive tyrosine-protein kinase PRAG1 (PEAK1-related kinase-activating pseudokinase 1) (Pragmin) (Sugen kinase 223) (SgK223)

Gene: PRAG1
Organism: Homo sapiens
Interactions: 29
UniProt ID: Q86YV5

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005925 - focal adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

834204

CSK
Tyrosine-protein kinase CSK

3

4

Small-scale

0.853

High

855673

CRK
Adapter molecule crk

3

9

High-throughput

0.839

High

855897

CRKL
Crk-like protein

2

12

High-throughput

0.811

High

987750

GRB2
Growth factor receptor-bound protein 2

3

8

High-throughput

0.805

High

966570

1433G
14-3-3 protein gamma

2

12

High-throughput

0.776

High

1049520

1433F
14-3-3 protein eta

2

12

High-throughput

0.776

High

730741

1433S
14-3-3 protein sigma

2

12

High-throughput

0.754

High

971742

1433E
14-3-3 protein epsilon

2

1

Small-scale

0.754

High

461671

HS90A
Heat shock protein HSP 90-alpha

1

2

High-throughput

0.618

High

468564

HS90B
Heat shock protein HSP 90-beta

1

2

High-throughput

0.618

High

1224849

TENS2
Tensin-2

1

1

High-throughput

0.618

High

1228511

TENS3
Tensin-3

1

1

High-throughput

0.618

High

1254502

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.586

High

878500

PAXI
Paxillin

2

1

High-throughput

0.584

High

691207

1433T
14-3-3 protein theta

1

12

High-throughput

0.575

High

730027

1433B
14-3-3 protein beta/alpha

1

12

High-throughput

0.575

High

786707

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

2

3

High-throughput

0.571

High

1050471

UBE3A
Ubiquitin-protein ligase E3A

1

0

High-throughput

0.486

High

1062258

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

1

High-throughput

0.479

High

1254039

PEAK3
Protein PEAK3

1

2

Small-scale

0.479

High

1295625

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1113610

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1295628

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1295629

XPO7
Exportin-7

1

0

High-throughput

0.458

High

1258492

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

1

High-throughput

0.445

High

1295626

ZMY19
Zinc finger MYND domain-containing protein 19

1

1

High-throughput

0.445

High

421167

SCG1
Secretogranin-1

1

0

High-throughput

0.282

High

458699

SAP
Prosaposin

1

0

High-throughput

0.282

High

1295627

SNAG
Gamma-soluble NSF attachment protein

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025