HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: PKHO2 (Q8TD55)
Pleckstrin homology domain-containing family O member 2 (PH domain-containing family O member 2) (Pleckstrin homology domain-containing family Q member 1) (PH domain-containing family Q member 1)
Gene: PLEKHO2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 490
+	Hs
		971811 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		PKHO2_HUMAN (1-490): 1.85e-74: 244: 100.00
+	Hs
		990529 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		PKHO2_HUMAN (1-490): 1.85e-74: 244: 100.00
+	Hs
		730079 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		PKHO2_HUMAN (1-490): 1.85e-74: 244: 100.00
+	Hs
		971417 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		ANK2_HUMAN (3-466): 4.01e-29: 124: 14.35
+	Hs
		690915 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		ANK2_HUMAN (3-466): 4.01e-29: 124: 14.35
+	Mm
		999147 1433F_MOUSE (2-242): 4.64e-106: 308: 71.43		PKHO2_MOUSE (1-490): 4.62e-63: 214: 70.71
+	Hs
		990109 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		ANK2_HUMAN (3-466): 4.01e-29: 124: 14.35
+	Hs
		971678 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		OTOG_HUMAN (74-467): 3.71e-17: 87.2: 11.55
+	Hs
		319058 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		K0754_HUMAN (95-490): 1.3e-16: 85.3: 12.26
+	Hs
		691153 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		OTOG_HUMAN (74-467): 3.71e-17: 87.2: 11.55
+	Hs
		990385 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		OTOG_HUMAN (74-467): 3.71e-17: 87.2: 11.55
+	Hs
		319061 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		K0754_HUMAN (95-490): 1.3e-16: 85.3: 12.26
+	Hs
		729976 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		OTOG_HUMAN (74-467): 3.71e-17: 87.2: 11.55
+	Hs
		319052 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		K0754_HUMAN (95-490): 1.3e-16: 85.3: 12.26
+	Hs
		690833 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		RGS3_HUMAN (230-426): 1.16e-12: 72.8: 18.66
+	Hs
		890644 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		RGS3_HUMAN (230-426): 1.16e-12: 72.8: 18.66
+	Hs
		729684 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		RGS3_HUMAN (230-426): 1.16e-12: 72.8: 18.66
+	Hs
		691291 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		TITIN_HUMAN (218-488): 7.96e-09: 60.6: 9.93
+	Hs
		990550 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		TITIN_HUMAN (218-488): 7.96e-09: 60.6: 9.93
+	Hs
		215918 1433F_HUMAN (2-242): 7.19e-106: 307: 71.43		SYNJ1_HUMAN (159-490): 4.43e-13: 74.1: 13.86