HitPredict

Interactor 1: MYO4 (P32492)
Myosin-4 (SWI5-dependent HO expression protein 1)
Gene: MYO4

Interactor 2: BRE1 (Q07457)
E3 ubiquitin-protein ligase BRE1 (EC 2.3.2.27) (Brefeldin A-sensitivity protein 1) (RING-type E3 ubiquitin transferase BRE1)
Gene: BRE1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	21179020
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1471 Sc			1 700
+	Sc
		585380 MYO2_YEAST (1-1428): 0: 1103: 48.58		BRE1_YEAST (1-700): 9.24e-50: 187: 100.00
+	Dm
		1303383 MYO7A_DROME (1-966): 0: 932: 32.89		MYSN_DROME (228-666): 6.66e-13: 74.7: 9.46
+	Hs
		725035 MYO5C_HUMAN (703-1435): 1.32e-47: 189: 12.71		MYH9_HUMAN (305-666): 1.45e-16: 86.6: 7.69
+	Hs
		1268099 MYO5C_HUMAN (703-1435): 1.32e-47: 189: 12.71		MY18A_HUMAN (76-573): 1.31e-13: 77: 10.67
+	Hs
		725065 MYO5B_HUMAN (704-1435): 3.48e-42: 172: 11.71		MYH9_HUMAN (305-666): 1.45e-16: 86.6: 7.69
+	Hs
		725086 MYO5A_HUMAN (717-1430): 3.69e-41: 168: 9.05		MYH9_HUMAN (305-666): 1.45e-16: 86.6: 7.69
+	Hs
		1268114 MYO5B_HUMAN (704-1435): 3.48e-42: 172: 11.71		MY18A_HUMAN (76-573): 1.31e-13: 77: 10.67
+	Hs
		1268124 MYO5A_HUMAN (717-1430): 3.69e-41: 168: 9.05		MY18A_HUMAN (76-573): 1.31e-13: 77: 10.67
+	Hs
		1343920 MYO5A_HUMAN (717-1430): 3.69e-41: 168: 9.05		MYO5C_HUMAN (86-475): 3.22e-12: 72.3: 12.75
+	Hs
		724810 MYH9_HUMAN (798-1108): 8.36e-09: 62.7: 12.18		ROCK1_HUMAN (141-637): 1.52e-25: 115: 13.87
+	Hs
		522585 MYH7_HUMAN (692-1134): 1.62e-15: 84.7: 7.02		MYH7_HUMAN (4-511): 1.08e-17: 90.1: 10.29
+	Rn
		361106 MYH6_RAT (759-1109): 2.31e-13: 77.8: 9.86		MYH6_RAT (4-521): 1.55e-17: 89.7: 10.28
+	Hs
		502901 MYH6_HUMAN (759-1109): 5.7e-14: 79.7: 8.22		MYH3_HUMAN (2-437): 1.4e-12: 73.5: 10.31
+	Hs
		522657 MYH7_HUMAN (692-1134): 1.62e-15: 84.7: 7.02		MYH4_HUMAN (291-661): 7.81e-11: 67.8: 9.74
+	Hs
		148466 MYH11_HUMAN (720-1116): 9.92e-10: 65.8: 11.00		CTRO_HUMAN (137-615): 1.43e-16: 86.6: 10.00
+	Hs
		725097 MYH11_HUMAN (720-1116): 9.92e-10: 65.8: 11.00		MYH10_HUMAN (245-667): 3.3e-16: 85.5: 10.88
+	Hs
		528356 MYH6_HUMAN (759-1109): 5.7e-14: 79.7: 8.22		MYH6_HUMAN (291-661): 1.01e-11: 70.9: 10.53
+	Hs
		148460 MYH9_HUMAN (798-1108): 8.36e-09: 62.7: 12.18		CTRO_HUMAN (137-615): 1.43e-16: 86.6: 10.00
+	Hs
		724686 MYH9_HUMAN (798-1108): 8.36e-09: 62.7: 12.18		MYH9_HUMAN (305-666): 1.45e-16: 86.6: 7.69
+	Hs
		724687 MYH9_HUMAN (798-1108): 8.36e-09: 62.7: 12.18		MYH10_HUMAN (245-667): 3.3e-16: 85.5: 10.88