Protein: SPIR2
Protein spire homolog 2 (Spir-2)

Gene: SPIR2, SPIRE2
Organism: Homo sapiens
Interactions: 17
UniProt ID: Q8WWL2

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005938 - cell cortex
GO:0008017 - microtubule binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

691283

1433T
14-3-3 protein theta

3

13

High-throughput

0.650

High

730095

1433B
14-3-3 protein beta/alpha

3

13

High-throughput

0.650

High

966674

1433G
14-3-3 protein gamma

3

13

High-throughput

0.650

High

1049612

1433F
14-3-3 protein eta

3

13

High-throughput

0.650

High

1196893

BCL7A
B-cell CLL/lymphoma 7 protein family member A

2

3

High-throughput

0.628

High

1359562

TMOD3
Tropomodulin-3

2

1

High-throughput

0.628

High

990543

1433Z
14-3-3 protein zeta/delta

2

13

High-throughput

0.611

High

169670

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

0

High-throughput

0.580

High

952988

ACTB
Actin, cytoplasmic 1

1

5

High-throughput

0.536

High

993269

ACTG
Actin, cytoplasmic 2

1

5

High-throughput

0.536

High

1357455

BCL7C
B-cell CLL/lymphoma 7 protein family member C

1

3

High-throughput

0.536

High

913548

KIF11
Kinesin-like protein KIF11

1

0

High-throughput

0.513

High

1359561

MPP8
M-phase phosphoprotein 8

1

0

High-throughput

0.513

High

730796

1433S
14-3-3 protein sigma

1

13

High-throughput

0.479

High

971829

1433E
14-3-3 protein epsilon

1

1

High-throughput

0.479

High

976453

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

106352

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025