HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: EDC3 (Q96F86)
Enhancer of mRNA-decapping protein 3 (LSM16 homolog) (YjeF N-terminal domain-containing protein 2) (YjeF_N2) (hYjeF_N2) (YjeF domain-containing protein 1)
Gene: EDC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.706

Property	Details
Experiments	17353931, 33961781, 36931259, 28514442, unassigned3799
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 508
+	Hs
		971869 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		EDC3_HUMAN (1-508): 0: 846: 100.00
+	Hs
		990594 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		EDC3_HUMAN (1-508): 0: 846: 100.00
+	Hs
		730138 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		EDC3_HUMAN (1-508): 0: 846: 100.00
+	Mm
		972288 1433E_MOUSE (2-243): 1.32e-144: 406: 63.53		EDC3_MOUSE (1-508): 0: 826: 95.67
+	Hs
		730820 1433S_HUMAN (1-236): 9.9e-108: 312: 71.85		EDC3_HUMAN (1-508): 0: 846: 100.00
+	Hs
		1049656 1433F_HUMAN (2-242): 7.19e-106: 307: 71.43		EDC3_HUMAN (1-508): 0: 846: 100.00
+	Hs
		966728 1433G_HUMAN (1-242): 5.51e-105: 305: 70.33		EDC3_HUMAN (1-508): 0: 846: 100.00