HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: LIMA1 (Q9UHB6)
LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)
Gene: LIMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	36931259, 15161933
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 759
+	Hs
		972102 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		990840 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		730331 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		730942 1433S_HUMAN (1-236): 9.9e-108: 312: 71.85		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		1049882 1433F_HUMAN (2-242): 7.19e-106: 307: 71.43		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		966987 1433G_HUMAN (1-242): 5.51e-105: 305: 70.33		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		971774 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		MILK1_HUMAN (355-540): 3.06e-31: 133: 21.81
+	Hs
		990490 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		MILK1_HUMAN (355-540): 3.06e-31: 133: 21.81
+	Hs
		730050 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		MILK1_HUMAN (355-540): 3.06e-31: 133: 21.81
+	Hs
		159180 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		ABLM1_HUMAN (298-548): 7.07e-23: 106: 11.28
+	Hs
		159153 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		ABLM1_HUMAN (298-548): 7.07e-23: 106: 11.28
+	Hs
		159184 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		ABLM1_HUMAN (298-548): 7.07e-23: 106: 11.28
+	Hs
		159159 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		ABLM1_HUMAN (298-548): 7.07e-23: 106: 11.28
+	Hs
		1049551 1433F_HUMAN (2-242): 7.19e-106: 307: 71.43		MILK1_HUMAN (355-540): 3.06e-31: 133: 21.81
+	Hs
		966605 1433G_HUMAN (1-242): 5.51e-105: 305: 70.33		MILK1_HUMAN (355-540): 3.06e-31: 133: 21.81
+	Hs
		159160 1433S_HUMAN (1-236): 9.9e-108: 312: 71.85		ABLM1_HUMAN (298-548): 7.07e-23: 106: 11.28
+	Hs
		159190 1433F_HUMAN (2-242): 7.19e-106: 307: 71.43		ABLM1_HUMAN (298-548): 7.07e-23: 106: 11.28
+	Hs
		159177 1433G_HUMAN (1-242): 5.51e-105: 305: 70.33		ABLM1_HUMAN (298-548): 7.07e-23: 106: 11.28
+	Hs
		730590 1433S_HUMAN (1-236): 9.9e-108: 312: 71.85		LASP1_HUMAN (390-480): 2.67e-11: 66.8: 25.00