Interactor 1: ZO1 (Q07157)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1

Interactor 2: SRC8 (Q14247)
Src substrate cortactin (Amplaxin) (Oncogene EMS1)
Gene: CTTN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SH3_2~SH3_9
Common GO terms GO:0002102 - podosome
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0030036 - actin cytoskeleton organization
and 1 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1748
Hs

1 550
+ Mm
+ Hs
+ Dm
+ Dm
+ Hs
+ Mm
+ Mm
+ Mm
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+ Hs
+ Hs

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Last updated: 15 Jul 2024