HitPredict

Interactor 1: PP12 (P32598)
Serine/threonine-protein phosphatase PP1-2 (EC 3.1.3.16)
Gene: GLC7

Interactor 2: YSH1 (Q06224)
Endoribonuclease YSH1 (EC 3.1.27.-) (Yeast 73 kDa homolog 1) (mRNA 3'-end-processing protein YSH1)
Gene: YSH1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.733

Property	Details
Experiments	11805826, 16429126, 11841235, 16137619, 37968396, 21179020
Identification Methods	tandem affinity purification, affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex GO:0030846 - termination of RNA polymerase II transcription, poly(A)-coupled GO:0046872 - metal ion binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 312 Sc			1 779
+	Sp
		142959 PP11_SCHPO (1-311): 0: 548: 85.85		YSH1_SCHPO (2-778): 0: 629: 47.11
+	Hs
		915213 PP2AB_HUMAN (7-300): 1.58e-175: 489: 46.44		INT11_HUMAN (7-625): 0: 553: 28.82
+	Sc
		696427 PP12_YEAST (1-312): 0: 565: 100.00		CFT2_YEAST (15-546): 2.92e-90: 304: 14.74
+	Sp
		251802 PP11_SCHPO (1-311): 0: 548: 85.85		CFT2_SCHPO (26-546): 1.02e-86: 293: 18.00
+	Hs
		915289 PP2AB_HUMAN (7-300): 1.58e-175: 489: 46.44		INT9_HUMAN (9-535): 9.34e-98: 319: 16.80
+	Sc
		696422 PP12_YEAST (1-312): 0: 565: 100.00		SYC1_YEAST (569-779): 1.58e-37: 140: 33.65