Interactor 1: ATC5 (P32660)
Phospholipid-transporting ATPase DNF1 (EC 7.6.2.1) (Flippase DNF1)
Gene: DNF1

Interactor 2: LEM3 (P42838)
Phospholipid-transporting ATPase accessory subunit LEM3 (Alkylphosphocholine resistance protein LEM3) (Brefeldin-A sensitivity protein 3) (Ro-sensitive 3)
Gene: LEM3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 33320091, 19968326, 16600184, 18467557, 35294892, 37968396, 15090616, 22791719
Identification Methods biochemical, x-ray crystallography, two hybrid, affinity chromatography technology, protein complementation assay, anti bait coimmunoprecipitation, ubiquitin reconstruction, anti tag coimmunoprecipitation, dihydrofolate reductase reconstruction
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC50~PhoLip_ATPase_C, CDC50~PhoLip_ATPase_N
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
GO:0045332 - phospholipid translocation
GO:1990531 - phospholipid-translocating ATPase complex
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1571
Sc

1 414
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Last updated: 15 Jul 2024