HitPredict

Interactor 1: GSP1 (P32835)
GTP-binding nuclear protein GSP1/CNR1 (Chromosome stability protein 17) (GTPase Ran homolog) (Genetic suppressor of PRP20-1)
Gene: GSP1

Interactor 2: SXM1 (Q04175)
Importin beta SMX1 (Suppressor of mRNA export mutant protein 1) (karyopherin-108)
Gene: SXM1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	21329658
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Cse1~Ras, IBN_N~Ras
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006606 - protein import into nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 219 Sc			1 944
+	Hs
		312234 RAN_HUMAN (1-216): 3.71e-76: 230: 80.56		IPO7_HUMAN (2-943): 0: 616: 21.07
+	Hs
		178143 RAN_HUMAN (1-216): 3.71e-76: 230: 80.56		IPO8_HUMAN (2-943): 0: 595: 19.71
+	Hs
		874484 RAN_HUMAN (1-216): 3.71e-76: 230: 80.56		XPO2_HUMAN (3-942): 1.7e-160: 497: 15.92
+	Dm
		1373317 RANL_DROME (13-219): 2.1e-90: 266: 59.42		Q9VRV8_DROME (4-837): 4.21e-142: 447: 11.24
+	At
		784988 RAN1_ARATH (1-216): 6.84e-94: 275: 75.58		TNPO1_ARATH (4-840): 3.39e-131: 418: 12.97
+	Hs
		919198 RAN_HUMAN (1-216): 3.71e-76: 230: 80.56		TNPO1_HUMAN (12-837): 1.49e-147: 462: 11.29
+	Hs
		127238 RAN_HUMAN (1-216): 3.71e-76: 230: 80.56		IPO5_HUMAN (3-924): 8.08e-142: 452: 10.23
+	Hs
		155560 RAN_HUMAN (1-216): 3.71e-76: 230: 80.56		TNPO2_HUMAN (12-837): 3.72e-140: 442: 10.62
+	At
		784992 RAN1_ARATH (1-216): 6.84e-94: 275: 75.58		IMB1_ARATH (6-769): 2.11e-123: 397: 13.02
+	Sc
		698861 GSP1_YEAST (1-219): 1.49e-79: 239: 100.00		NMD5_YEAST (2-940): 3.41e-133: 428: 23.62
+	At
		784999 RAN2_ARATH (1-216): 1.74e-88: 261: 75.58		IMB1_ARATH (6-769): 2.11e-123: 397: 13.02
+	Sc
		698750 GSP1_YEAST (1-219): 1.49e-79: 239: 100.00		CSE1_YEAST (1-938): 5.8e-130: 417: 16.35
+	Sc
		698999 GSP2_YEAST (1-219): 9.33e-78: 234: 96.82		CSE1_YEAST (1-938): 5.8e-130: 417: 16.35
+	At
		1210454 RAN3_ARATH (1-219): 5.37e-84: 250: 74.55		IMB1_ARATH (6-769): 2.11e-123: 397: 13.02
+	Hs
		236414 RB11A_HUMAN (1-207): 4.63e-79: 237: 26.17		RNBP6_HUMAN (1-924): 5.96e-126: 410: 10.20
+	Sp
		142272 SPI1_SCHPO (5-219): 6.33e-77: 232: 88.37		CSE1_SCHPO (5-937): 2.67e-122: 397: 16.12
+	Hs
		919222 RAN_HUMAN (1-216): 3.71e-76: 230: 80.56		IPO9_HUMAN (4-898): 1.49e-118: 388: 12.77
+	Sc
		698917 GSP1_YEAST (1-219): 1.49e-79: 239: 100.00		KA120_YEAST (2-943): 1.73e-110: 366: 15.42
+	Sc
		699016 GSP2_YEAST (1-219): 9.33e-78: 234: 96.82		KA120_YEAST (2-943): 1.73e-110: 366: 15.42
+	Sc
		698878 GSP1_YEAST (1-219): 1.49e-79: 239: 100.00		IMB5_YEAST (7-898): 3.44e-23: 108: 11.99