HitPredict

Interactor 1: GSP1 (P32835)
GTP-binding nuclear protein GSP1/CNR1 (Chromosome stability protein 17) (GTPase Ran homolog) (Genetic suppressor of PRP20-1)
Gene: GSP1

Interactor 2: DOA1 (P36037)
Protein DOA1 (Degradation of alpha protein 1) (Ubiquitin fusion degradation protein 3)
Gene: DOA1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26349035
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 219 Sc			1 715
+	Sc
		699001 GSP2_YEAST (1-219): 9.33e-78: 234: 96.82		DOA1_YEAST (1-715): 0: 540: 100.00
+	Hs
		919313 RAN_HUMAN (1-216): 3.71e-76: 230: 80.56		FBW1A_HUMAN (124-459): 4.96e-44: 169: 15.79
+	Hs
		919203 RAN_HUMAN (1-216): 3.71e-76: 230: 80.56		FBXW7_HUMAN (205-534): 1.17e-40: 160: 14.63
+	Sc
		698776 GSP1_YEAST (1-219): 1.49e-79: 239: 100.00		TAF5_YEAST (89-302): 5.91e-19: 93.6: 32.74
+	Hs
		903100 RAB1A_HUMAN (1-207): 7e-82: 244: 28.10		WDR5_HUMAN (2-82): 7.4e-13: 72.3: 12.64
+	Hs
		903508 RAB1B_HUMAN (7-208): 3.73e-80: 239: 27.81		WDR5_HUMAN (2-82): 7.4e-13: 72.3: 12.64
+	Hs
		894711 RAB8A_HUMAN (6-211): 1.53e-76: 230: 26.32		WDR5_HUMAN (2-82): 7.4e-13: 72.3: 12.64
+	Hs
		903101 RAN_HUMAN (1-216): 3.71e-76: 230: 80.56		WDR5_HUMAN (2-82): 7.4e-13: 72.3: 12.64
+	Hs
		845339 RAB7A_HUMAN (13-168): 4.23e-28: 107: 33.74		FBW1B_HUMAN (99-329): 3.03e-45: 171: 23.53
+	Hs
		895570 RAB10_HUMAN (13-170): 3.23e-28: 107: 34.16		FBW1A_HUMAN (124-459): 4.96e-44: 169: 15.79
+	Hs
		844465 RAB5C_HUMAN (2-183): 8.7e-29: 108: 34.05		WDR5_HUMAN (2-82): 7.4e-13: 72.3: 12.64