HitPredict

Interactor 1: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Interactor 2: DJB12 (Q9NXW2)
DnaJ homolog subfamily B member 12
Gene: DNAJB12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33957083, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane GO:0031965 - nuclear membrane GO:0036503 - ERAD pathway
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 592 Hs			1 375
+	Hs
		699228 CALX_HUMAN (1-592): 0: 786: 100.00		SEC63_HUMAN (87-373): 4.78e-51: 183: 18.61
+	Hs
		699222 CALX_HUMAN (1-592): 0: 786: 100.00		DJB11_HUMAN (101-368): 1.56e-46: 164: 23.49
+	Hs
		699221 CALX_HUMAN (1-592): 0: 786: 100.00		DNJB9_HUMAN (99-247): 1.08e-41: 147: 32.89
+	Rn
		772453 CALX_RAT (1-592): 0: 740: 91.06		DNJB9_RAT (102-239): 6.84e-46: 158: 33.81
+	Hs
		698049 CALR_HUMAN (67-470): 1.2e-141: 418: 38.33		DJB12_HUMAN (1-375): 1.34e-139: 403: 100.00
+	Hs
		1396548 CALR3_HUMAN (64-470): 4.24e-135: 400: 26.59		DJB12_HUMAN (1-375): 1.34e-139: 403: 100.00
+	Dm
		1468088 Q9VAL7_DROME (33-592): 0: 633: 49.74		Q9VS57_DROME (57-373): 1.73e-43: 162: 16.22
+	Hs
		1396554 CALR3_HUMAN (64-470): 4.24e-135: 400: 26.59		SEC63_HUMAN (87-373): 4.78e-51: 183: 18.61
+	Hs
		698060 CALR_HUMAN (67-470): 1.2e-141: 418: 38.33		DJB11_HUMAN (101-368): 1.56e-46: 164: 23.49
+	Hs
		698059 CALR_HUMAN (67-470): 1.2e-141: 418: 38.33		DNJB9_HUMAN (99-247): 1.08e-41: 147: 32.89
+	Hs
		1396552 CALR3_HUMAN (64-470): 4.24e-135: 400: 26.59		DJB11_HUMAN (101-368): 1.56e-46: 164: 23.49