HitPredict

Interactor 1: PEP12 (P32854)
Syntaxin PEP12 (Carboxypeptidase Y-deficient protein 12) (Vacuolar protein sorting-associated protein 6) (Vacuolar protein-targeting protein 13)
Gene: PEP12

Interactor 2: VTI1 (Q04338)
t-SNARE VTI1 (Qb-SNARE VTI1) (VPS10-interacting protein 1) (Vesicle transport v-SNARE protein VTI1)
Gene: VTI1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.924

The method score is based on:

Property Details
Experiments 9199167, 11283351, 10655498, 14981247, 23776654
Identification Methods affinity chromatography technology, coimmunoprecipitation, two hybrid pooling approach, two hybrid, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SNARE~V-SNARE_C
Common GO terms GO:0000139 - Golgi membrane
GO:0000149 - SNARE binding
GO:0000329 - fungal-type vacuole membrane
GO:0005484 - SNAP receptor activity
GO:0005794 - Golgi apparatus
and 9 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 288
Sc

1 217
+ At
+ At
+ Mm
+ At
+ At
+ At
+ At
+ Hs
+ Dm
+ Mm
+ Dm
+ Mm
+ Dm
+ Hs
+ Dm
+ Dm
+ Ce
+ Dm
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024