Interactor 1: SC61A (P32915)
Protein transport protein SEC61 (Sec61 complex subunit SEC61) (Sec61 complex subunit alpha)
Gene: SEC61

Interactor 2: SC61G (P35179)
Protein transport protein SSS1 (Sec61 complex subunit SSS1) (Sec61 complex subunit gamma) (Ssh1 complex subunit SSS1) (Ssh1 complex subunit gamma)
Gene: SSS1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 7961662, 9303299, 23237413, 11576447, 30682149, 20709746, 23044417, 23497013, 8612571
Identification Methods coimmunoprecipitation, cross-linking study, affinity chromatography technology, biochemical, protein complementation assay, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Plug_translocon~SecE, SecE~SecY
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005784 - Sec61 translocon complex
GO:0006616 - SRP-dependent cotranslational protein targeting to membrane, translocation
GO:0008320 - protein transmembrane transporter activity
GO:0030867 - rough endoplasmic reticulum membrane
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 480
Sc

1 80
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024