Interactor 1: 5HT2A (P28223)
5-hydroxytryptamine receptor 2A (5-HT-2) (5-HT-2A) (Serotonin receptor 2A)
Gene: HTR2A
Interactor 2: GRM2 (Q14416)
Metabotropic glutamate receptor 2 (mGluR2)
Gene: GRM2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.57 | 0.60 | 0.589 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18297054 |
| Identification Methods | anti tag coimmunoprecipitation, fluorescent resonance energy transfer, anti bait coimmunoprecipitation, bioluminescence resonance energy transfer |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005886 - plasma membrane GO:0007268 - chemical synaptic transmission GO:0014059 - regulation of dopamine secretion GO:0030424 - axon GO:0030425 - dendrite and 4 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
