Interactor 1: SC61A (P32915)
Protein transport protein SEC61 (Sec61 complex subunit SEC61) (Sec61 complex subunit alpha)
Gene: SEC61

Interactor 2: SC6B1 (P52870)
Protein transport protein SBH1 (Sec61 complex subunit SBH1) (Sec61 complex subunit beta)
Gene: SBH1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 7758110, 31201345, 17699516, 19365066, 19857245, 11576447, 29986881, 23497013, 8612571
Identification Methods affinity chromatography technology, two hybrid, biochemical, pull down, protein complementation assay, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Plug_translocon~Sec61_beta, Sec61_beta~SecY
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005784 - Sec61 translocon complex
GO:0006616 - SRP-dependent cotranslational protein targeting to membrane, translocation
GO:0008320 - protein transmembrane transporter activity
GO:0030867 - rough endoplasmic reticulum membrane
and 2 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 480
Sc

1 82
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024