HitPredict

Interactor 1: UFD4 (P33202)
Ubiquitin fusion degradation protein 4 (UB fusion protein 4) (EC 2.3.2.-) (HECT-type E3 ubiquitin transferase UFD4) (EC 2.3.2.26)
Gene: UFD4

Interactor 2: PSA4 (P40303)
Proteasome subunit alpha type-4 (Macropain subunit PRE6) (Multicatalytic endopeptidase complex subunit PRE6) (Proteasome component PRE6) (Proteinase YSCE subunit PRE6)
Gene: PRE6

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12447385
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005739 - mitochondrion GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1483 Sc			1 254
+	Hs
		638201 SMUF1_HUMAN (965-1479): 4.08e-162: 509: 17.15		PSA4_HUMAN (3-233): 8.68e-91: 270: 31.49
+	Hs
		656320 SMUF1_HUMAN (965-1479): 4.08e-162: 509: 17.15		PSA5_HUMAN (2-236): 2.2e-90: 268: 32.92
+	Hs
		638134 HERC3_HUMAN (826-1481): 1.62e-149: 485: 19.36		PSA4_HUMAN (3-233): 8.68e-91: 270: 31.49
+	Sc
		619384 TOM1_YEAST (595-1483): 1.37e-167: 562: 16.87		PSA3_YEAST (4-207): 3.34e-40: 140: 35.29
+	Hs
		893675 UBE3C_HUMAN (1185-1478): 1.15e-26: 120: 29.43		PSA6_HUMAN (2-239): 6.82e-91: 270: 29.75
+	Hs
		637427 UBE3C_HUMAN (1185-1478): 1.15e-26: 120: 29.43		PSA1_HUMAN (2-249): 6.06e-90: 268: 31.35
+	Hs
		656235 UBE3C_HUMAN (1185-1478): 1.15e-26: 120: 29.43		PSA5_HUMAN (2-236): 2.2e-90: 268: 32.92
+	Hs
		156275 UBE3A_HUMAN (1204-1482): 2.39e-21: 103: 29.17		PSA7_HUMAN (4-234): 3.74e-95: 280: 58.01
+	Hs
		156320 HUWE1_HUMAN (1191-1483): 1.44e-20: 101: 31.51		PSA7_HUMAN (4-234): 3.74e-95: 280: 58.01
+	Hs
		638114 UBE3A_HUMAN (1204-1482): 2.39e-21: 103: 29.17		PSA4_HUMAN (3-233): 8.68e-91: 270: 31.49
+	Hs
		893654 UBE3A_HUMAN (1204-1482): 2.39e-21: 103: 29.17		PSA6_HUMAN (2-239): 6.82e-91: 270: 29.75
+	Hs
		637394 UBE3A_HUMAN (1204-1482): 2.39e-21: 103: 29.17		PSA1_HUMAN (2-249): 6.06e-90: 268: 31.35
+	Hs
		638160 HUWE1_HUMAN (1191-1483): 1.44e-20: 101: 31.51		PSA4_HUMAN (3-233): 8.68e-91: 270: 31.49
+	Hs
		656207 UBE3A_HUMAN (1204-1482): 2.39e-21: 103: 29.17		PSA5_HUMAN (2-236): 2.2e-90: 268: 32.92
+	Hs
		893701 HUWE1_HUMAN (1191-1483): 1.44e-20: 101: 31.51		PSA6_HUMAN (2-239): 6.82e-91: 270: 29.75
+	Hs
		637468 HUWE1_HUMAN (1191-1483): 1.44e-20: 101: 31.51		PSA1_HUMAN (2-249): 6.06e-90: 268: 31.35
+	Hs
		656264 HUWE1_HUMAN (1191-1483): 1.44e-20: 101: 31.51		PSA5_HUMAN (2-236): 2.2e-90: 268: 32.92
+	Hs
		637692 UBE3C_HUMAN (1185-1478): 1.15e-26: 120: 29.43		PSA2_HUMAN (3-236): 1.56e-45: 154: 38.14
+	Hs
		637675 UBE3A_HUMAN (1204-1482): 2.39e-21: 103: 29.17		PSA2_HUMAN (3-236): 1.56e-45: 154: 38.14
+	Hs
		637712 HUWE1_HUMAN (1191-1483): 1.44e-20: 101: 31.51		PSA2_HUMAN (3-236): 1.56e-45: 154: 38.14