HitPredict

Interactor 1: SMCA1 (P28370)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1 (SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A1) (EC 3.6.4.-) (Global transcription activator SNF2L1) (Nucleosome-remodeling factor subunit SNF2L) (SNF2L) (SNF2 related chromatin remodeling ATPase 1)
Gene: SMARCA1

Interactor 2: CGAS (Q8N884)
Cyclic GMP-AMP synthase (cGAMP synthase) (cGAS) (h-cGAS) (EC 2.7.7.86) (2'3'-cGAMP synthase) (Mab-21 domain-containing protein 1)
Gene: CGAS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30471916
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 1 others more... GO:0031491 - nucleosome binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1042 Hs			1 522
+	Hs
		243680 SMCA5_HUMAN (32-1037): 0: 995: 82.90		CGAS_HUMAN (1-522): 0: 680: 100.00
+	Hs
		160193 CHD2_HUMAN (14-1040): 0: 703: 29.42		CGAS_HUMAN (1-522): 0: 680: 100.00
+	Hs
		160110 CHD1_HUMAN (5-1041): 0: 671: 28.96		CGAS_HUMAN (1-522): 0: 680: 100.00
+	Hs
		1133075 CHD4_HUMAN (32-942): 0: 758: 28.87		MB212_HUMAN (158-512): 7.27e-125: 371: 20.21
+	Hs
		1331436 CHD7_HUMAN (3-1031): 0: 777: 26.63		MB213_HUMAN (168-492): 7.66e-83: 263: 23.60
+	Hs
		1331430 CHD8_HUMAN (2-1031): 0: 761: 26.87		MB213_HUMAN (168-492): 7.66e-83: 263: 23.60
+	Hs
		1186493 CHD9_HUMAN (2-1007): 0: 731: 27.15		MB213_HUMAN (168-492): 7.66e-83: 263: 23.60