HitPredict

Interactor 1: GCYA2 (P33402)
Guanylate cyclase soluble subunit alpha-2 (GCS-alpha-2) (EC 4.6.1.2)
Gene: GUCY1A2

Interactor 2: SCRIB (Q14160)
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Gene: SCRIB

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.50	0.567

Property	Details
Experiments	24550280, 30126976
Identification Methods	affinity chromatography technology, phage display, anti tag coimmunoprecipitation, p8 filamentous phage display
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 1630
+	Rn
		677808 GCYA2_RAT (1-732): 0: 906: 90.98		DLG4_RAT (812-1187): 3.08e-49: 190: 22.42
+	Hs
		704958 GCYA2_HUMAN (1-732): 0: 864: 100.00		DLG4_HUMAN (812-1187): 3.22e-49: 190: 22.42
+	Rn
		1144362 GCYA2_RAT (1-732): 0: 906: 90.98		DLG2_RAT (587-879): 2.66e-21: 103: 18.52
+	Rn
		1144082 GCYA2_RAT (1-732): 0: 906: 90.98		DLG3_RAT (724-947): 3.57e-19: 96.3: 31.23
+	Rn
		1144018 GCYA2_RAT (1-732): 0: 906: 90.98		DLG1_RAT (679-910): 1.87e-14: 80.9: 22.79
+	Hs
		704964 GCYA2_HUMAN (1-732): 0: 864: 100.00		DLG2_HUMAN (587-879): 1.21e-20: 101: 18.67
+	Hs
		704965 GCYA2_HUMAN (1-732): 0: 864: 100.00		DLG3_HUMAN (724-947): 1.74e-19: 97.4: 31.23
+	Hs
		704960 GCYA2_HUMAN (1-732): 0: 864: 100.00		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		704966 GCYA2_HUMAN (1-732): 0: 864: 100.00		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06
+	Rn
		594291 GCYB1_RAT (112-703): 0: 646: 33.87		DLG4_RAT (812-1187): 3.08e-49: 190: 22.42