Protein: TFDP1
Transcription factor Dp-1 (DRTF1-polypeptide 1) (DRTF1) (E2F dimerization partner 1)

Gene: TFDP1
Organism: Homo sapiens
Interactions: 121
UniProt ID: Q14186

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1029083

E2F1
Transcription factor E2F1

23

20

Small-scale

0.991

High

282714

E2F6
Transcription factor E2F6

13

20

Small-scale

0.985

High

1122832

E2F4
Transcription factor E2F4

11

20

Small-scale

0.976

High

442710

RB
Retinoblastoma-associated protein

6

11

Small-scale

0.949

High

1122826

E2F2
Transcription factor E2F2

6

20

Small-scale

0.938

High

1122830

E2F5
Transcription factor E2F5

5

20

Small-scale

0.919

High

143432

E2F3
Transcription factor E2F3

4

20

Small-scale

0.890

High

1122846

RYBP
RING1 and YY1-binding protein

6

2

High-throughput

0.732

High

959579

MAX
Protein max

5

3

Small-scale

0.723

High

1122863

PCGF6
Polycomb group RING finger protein 6

5

5

High-throughput

0.722

High

1122853

LMBL2
Lethal(3)malignant brain tumor-like protein 2

5

3

High-throughput

0.720

High

667842

CDK2
Cyclin-dependent kinase 2

4

7

Small-scale

0.702

High

1122844

YAF2
YY1-associated factor 2

4

2

High-throughput

0.699

High

1122866

COMD4
COMM domain-containing protein 4

4

1

High-throughput

0.699

High

1122870

COMD8
COMM domain-containing protein 8

4

1

High-throughput

0.697

High

284313

GEMI
Geminin

3

2

High-throughput

0.675

High

1109714

HDAC1
Histone deacetylase 1

3

1

High-throughput

0.675

High

1122848

COMD1
COMM domain-containing protein 1

3

1

High-throughput

0.675

High

704962

RBL1
Retinoblastoma-like protein 1

1

11

Small-scale

0.665

High

1122855

LIN37
Protein lin-37 homolog

3

2

Small-scale

0.662

High

1122838

COMD6
COMM domain-containing protein 6

3

0

High-throughput

0.646

High

1122845

MIER2
Mesoderm induction early response protein 2

3

0

High-throughput

0.638

High

964941

WDR5
WD repeat-containing protein 5

2

1

High-throughput

0.628

High

1055803

RING1
E3 ubiquitin-protein ligase RING1

2

5

High-throughput

0.628

High

1097284

CBX3
Chromobox protein homolog 3

2

3

High-throughput

0.628

High

1122834

LIN9
Protein lin-9 homolog

2

2

Small-scale

0.628

High

1122843

MGAP
MAX gene-associated protein

2

1

High-throughput

0.628

High

413817

P53
Cellular tumor antigen p53

2

0

Small-scale

0.619

High

1122858

RING2
E3 ubiquitin-protein ligase RING2

2

5

High-throughput

0.611

High

537143

HSP7C
Heat shock cognate 71 kDa protein

2

0

High-throughput

0.602

High

1122876

GGA1
ADP-ribosylation factor-binding protein GGA1

2

0

High-throughput

0.602

High

1122851

CBP
CREB-binding protein

2

3

Small-scale

0.595

High

1122825

TFDP2
Transcription factor Dp-2

1

0

High-throughput

0.586

High

372004

MYC
Myc proto-oncogene protein

2

6

High-throughput

0.584

High

473981

NFIC
Nuclear factor 1 C-type

2

5

High-throughput

0.584

High

1122828

NFIX
Nuclear factor 1 X-type

2

5

High-throughput

0.584

High

155942

SOCS3
Suppressor of cytokine signaling 3

1

3

Small-scale

0.573

High

1065655

RBL2
Retinoblastoma-like protein 2

1

11

Small-scale

0.554

High

1025344

CDK6
Cyclin-dependent kinase 6

1

9

Small-scale

0.550

High

94480

MCIN
Multicilin

1

2

High-throughput

0.536

High

629121

CCNA2
Cyclin-A2

1

4

High-throughput

0.536

High

808062

CDN1A
Cyclin-dependent kinase inhibitor 1

1

1

High-throughput

0.536

High

899038

TCPQ
T-complex protein 1 subunit theta

1

1

High-throughput

0.536

High

1014095

CBX1
Chromobox protein homolog 1

1

3

High-throughput

0.536

High

1066300

RBBP4
Histone-binding protein RBBP4

1

2

High-throughput

0.536

High

1099880

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.536

High

1122835

LIN54
Protein lin-54 homolog

1

2

Small-scale

0.536

High

1122850

HDAC2
Histone deacetylase 2

1

1

High-throughput

0.536

High

229011

AKAP8
A-kinase anchor protein 8

1

0

High-throughput

0.513

High

321238

ERLN2
Erlin-2

1

0

High-throughput

0.513

High

329747

ZRAB2
Zinc finger Ran-binding domain-containing protein 2

1

0

High-throughput

0.513

High

359652

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

High-throughput

0.513

High

423775

APOD
Apolipoprotein D

1

0

High-throughput

0.513

High

598083

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

0

High-throughput

0.513

High

611861

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

701816

ABCD3
ATP-binding cassette sub-family D member 3

1

0

High-throughput

0.513

High

848620

MAGA9
Melanoma-associated antigen 9

1

0

High-throughput

0.513

High

875958

TCPE
T-complex protein 1 subunit epsilon

1

0

High-throughput

0.513

High

958768

ARF3
ADP-ribosylation factor 3

1

0

High-throughput

0.513

High

1122831

PCBP1
Poly(rC)-binding protein 1

1

0

High-throughput

0.513

High

1122836

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

High-throughput

0.513

High

1122839

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.513

High

1122859

DHB14
L-fucose dehydrogenase

1

0

High-throughput

0.513

High

1122860

TBA1C
Tubulin alpha-1C chain

1

0

High-throughput

0.513

High

1122864

COMD5
COMM domain-containing protein 5

1

0

High-throughput

0.513

High

1122867

CDT1
DNA replication factor Cdt1

1

0

High-throughput

0.513

High

1122872

GRHPR
Glyoxylate reductase/hydroxypyruvate reductase

1

0

High-throughput

0.513

High

1122874

DIC
Mitochondrial dicarboxylate carrier

1

0

High-throughput

0.513

High

185689

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.501

High

443360

CDK1
Cyclin-dependent kinase 1

1

7

Small-scale

0.501

High

1122841

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

1

High-throughput

0.481

High

384411

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.480

High

507959

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

842754

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

0

Small-scale

0.480

High

1088838

TP53B
TP53-binding protein 1

1

0

Small-scale

0.480

High

833735

KDM5C
Lysine-specific demethylase 5C

1

0

Small-scale

0.479

High

142991

NFIB
Nuclear factor 1 B-type

1

5

High-throughput

0.479

High

159347

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

2

Small-scale

0.479

High

180811

TIF1A
Transcription intermediary factor 1-alpha

1

3

High-throughput

0.479

High

190064

FOXP2
Forkhead box protein P2

1

2

Small-scale

0.479

High

258876

DNJA2
DnaJ homolog subfamily A member 2

1

2

High-throughput

0.479

High

339742

KLF8
Krueppel-like factor 8

1

3

High-throughput

0.479

High

666990

CCNE1
G1/S-specific cyclin-E1

1

7

Small-scale

0.479

High

679159

DNJB1
DnaJ homolog subfamily B member 1

1

3

High-throughput

0.479

High

703136

TEAD1
Transcriptional enhancer factor TEF-1

1

1

High-throughput

0.479

High

718562

CDC27
Cell division cycle protein 27 homolog

1

1

Small-scale

0.479

High

944651

KLF3
Krueppel-like factor 3

1

3

High-throughput

0.479

High

948148

DJB13
DnaJ homolog subfamily B member 13

1

3

High-throughput

0.479

High

1025265

CDK3
Cyclin-dependent kinase 3

1

7

Small-scale

0.479

High

1050735

MAD1
Max dimerization protein 1

1

4

Small-scale

0.479

High

1086850

CDC20
Cell division cycle protein 20 homolog

1

2

Small-scale

0.479

High

1087734

NFIA
Nuclear factor 1 A-type

1

5

High-throughput

0.479

High

1122829

BRD3
Bromodomain-containing protein 3

1

2

High-throughput

0.479

High

1122842

FOXP4
Forkhead box protein P4

1

2

Small-scale

0.479

High

1122849

NUP43
Nucleoporin Nup43

1

4

High-throughput

0.479

High

1122852

KAT6A
Histone acetyltransferase KAT6A

1

2

High-throughput

0.479

High

1122854

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

1

High-throughput

0.479

High

1122862

KLF16
Krueppel-like factor 16

1

2

High-throughput

0.479

High

1122868

FOXP1
Forkhead box protein P1

1

2

Small-scale

0.479

High

1122871

NLK
Serine/threonine-protein kinase NLK

1

6

Small-scale

0.479

High

1122877

KLF12
Krueppel-like factor 12

1

3

High-throughput

0.479

High

675496

TYY1
Transcriptional repressor protein YY1

1

0

High-throughput

0.458

High

685189

PAX6
Paired box protein Pax-6

1

0

High-throughput

0.458

High

1016848

H33
Histone H3.3

1

0

High-throughput

0.458

High

1122833

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1122837

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1122840

MIB1
E3 ubiquitin-protein ligase MIB1

1

0

High-throughput

0.458

High

1122857

CIC
Protein capicua homolog

1

0

High-throughput

0.458

High

1122865

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

1122873

ZMYM2
Zinc finger MYM-type protein 2

1

0

High-throughput

0.458

High

1122875

APC5
Anaphase-promoting complex subunit 5

1

0

Small-scale

0.458

High

159650

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

2

Small-scale

0.445

High

472309

CFAH
Complement factor H

1

1

Small-scale

0.437

High

1122847

FBXL6
F-box/LRR-repeat protein 6

1

1

High-throughput

0.437

High

181108

AXIN1
Axin-1

1

0

Small-scale

0.426

High

630272

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

0

High-throughput

0.279

Low

1122827

RCN2
Reticulocalbin-2

1

0

High-throughput

0.279

Low

1122856

ATPMK
ATP synthase F(0) complex subunit k, mitochondrial

1

0

High-throughput

0.279

Low

1122861

NTPCR
Cancer-related nucleoside-triphosphatase

1

0

High-throughput

0.279

Low

1122869

NPDC1
Neural proliferation differentiation and control protein 1

1

0

Small-scale

0.261

Low

105921

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025