HitPredict

Interactor 1: GCN1 (P33892)
eIF-2-alpha kinase activator GCN1 (General control non-derepressible protein 1) (Translational activator GCN1)
Gene: GCN1

Interactor 2: RUVB2 (Q12464)
RuvB-like protein 2 (RUVBL2) (EC 3.6.4.12) (TIP49-homology protein 2) (TIP49b homolog)
Gene: RVB2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	16429126, 26831523
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2672 Sc			1 471
+	Sc
		707923 GCN1_YEAST (1-2672): 0: 1798: 100.00		RUVB1_YEAST (8-448): 0: 624: 41.10
+	Sc
		561096 EF3A_YEAST (1321-1710): 6.99e-83: 299: 22.87		RUVB2_YEAST (1-471): 0: 707: 100.00
+	Sc
		561061 EF3A_YEAST (1321-1710): 6.99e-83: 299: 22.87		RUVB1_YEAST (8-448): 0: 624: 41.10
+	Sc
		866894 EF3B_YEAST (1321-1674): 3.58e-82: 297: 22.69		RUVB1_YEAST (8-448): 0: 624: 41.10
+	Sc
		997087 NEW1_YEAST (1361-1636): 7.06e-35: 149: 18.95		RUVB2_YEAST (1-471): 0: 707: 100.00
+	Sc
		978035 NEW1_YEAST (1361-1636): 7.06e-35: 149: 18.95		RUVB1_YEAST (8-448): 0: 624: 41.10
+	Hs
		1202192 CAND1_HUMAN (814-1469): 2.62e-09: 65.1: 13.54		RUVB1_HUMAN (10-448): 0: 658: 41.72
+	Sc
		715975 UTP20_YEAST (1367-2411): 3.05e-15: 85.2: 11.49		RUVB1_YEAST (8-448): 0: 624: 41.10