Interactor 1: MCM4 (P33991)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (CDC21 homolog) (P1-CDC21)
Gene: MCM4

Interactor 2: CDT1 (Q9H211)
DNA replication factor Cdt1 (Double parked homolog) (DUP)
Gene: CDT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 18162579
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CDT1_C~MCM, CDT1_C~MCM_lid, CDT1_C~MCM_OB
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0030174 - regulation of DNA-templated DNA replication initiation
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 863
Hs

1 546
+ Hs
+ Mm
+ Hs
+ Mm
+ Sp
+ Sp

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Last updated: 15 Jul 2024