Protein: YL278
Uncharacterized transcriptional regulatory protein YLR278C

Gene: YL278, YLR278C
Organism: Saccharomyces cerevisiae S288C
Interactions: 56
UniProt ID: Q05854

Gene Ontology (top 5):
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006351 - DNA-templated transcription
GO:0008270 - zinc ion binding
GO:0043565 - sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

364743

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.561

High

805871

ARO9
Aromatic amino acid aminotransferase 2

1

0

High-throughput

0.493

High

382350

H4
Histone H4

1

1

High-throughput

0.479

High

419507

H2A1
Histone H2A.1

1

1

High-throughput

0.479

High

419877

H2A2
Histone H2A.2

1

1

High-throughput

0.479

High

708202

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

764006

SPT10
Protein SPT10

1

1

High-throughput

0.479

High

826840

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

1044750

SCC2
Sister chromatid cohesion protein 2

1

2

High-throughput

0.479

High

444877

SIR3
Regulatory protein SIR3

1

1

High-throughput

0.470

High

576008

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.458

High

666547

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.458

High

684845

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.458

High

809413

STM1
Suppressor protein STM1

1

0

High-throughput

0.458

High

885089

RL4B
Large ribosomal subunit protein uL4B

1

0

High-throughput

0.458

High

381267

H2B1
Histone H2B.1

1

1

High-throughput

0.445

High

525167

HSP71
Heat shock protein SSA1

1

9

High-throughput

0.445

High

527695

HSP72
Heat shock protein SSA2

1

9

High-throughput

0.445

High

546300

SSB1
Ribosome-associated molecular chaperone SSB1

1

7

High-throughput

0.445

High

671132

SIS1
Protein SIS1

1

4

High-throughput

0.445

High

671560

SWI4
Regulatory protein SWI4

1

1

High-throughput

0.445

High

742409

HSP7F
Heat shock protein homolog SSE1

1

14

High-throughput

0.445

High

742950

HSP79
Heat shock protein homolog SSE2

1

14

High-throughput

0.445

High

819813

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.445

High

409786

RL24A
Large ribosomal subunit protein eL24A

1

1

High-throughput

0.437

High

433296

RL17A
Large ribosomal subunit protein uL22A

1

1

High-throughput

0.437

High

663724

RL24B
Large ribosomal subunit protein eL24B

1

1

High-throughput

0.437

High

863884

RL17B
Large ribosomal subunit protein uL22B

1

1

High-throughput

0.437

High

645646

AFT1
Iron-regulated transcriptional activator AFT1

1

0

High-throughput

0.426

High

912448

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

811040

TCPD
T-complex protein 1 subunit delta

1

1

High-throughput

0.407

High

1052541

HSP42
Heat shock protein 42

1

1

High-throughput

0.407

High

550695

SIR4
Regulatory protein SIR4

1

0

High-throughput

0.269

Low

917428

GPG1
Heterotrimeric G protein gamma subunit GPG1

1

0

High-throughput

0.269

Low

149959

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.249

Low

383199

RLA4
Large ribosomal subunit protein P2B

1

0

High-throughput

0.249

Low

432704

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.249

Low

432920

RL9A
Large ribosomal subunit protein uL6A

1

0

High-throughput

0.249

Low

434652

RL22A
Large ribosomal subunit protein eL22A

1

0

High-throughput

0.249

Low

455443

RS19B
Small ribosomal subunit protein eS19B

1

0

High-throughput

0.249

Low

512154

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.249

Low

515175

RL19B
Large ribosomal subunit protein eL19

1

0

High-throughput

0.249

Low

570145

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.249

Low

601133

RL8A
Large ribosomal subunit protein eL8A

1

0

High-throughput

0.249

Low

689139

RL16A
Large ribosomal subunit protein uL13A

1

0

High-throughput

0.249

Low

781264

RL14A
Large ribosomal subunit protein eL14A

1

0

High-throughput

0.249

Low

820966

RL13B
Large ribosomal subunit protein eL13B

1

0

High-throughput

0.249

Low

835893

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.249

Low

858069

RSSA2
Small ribosomal subunit protein uS2B

1

0

High-throughput

0.249

Low

870684

RS7B
Small ribosomal subunit protein eS7B

1

0

High-throughput

0.249

Low

879895

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.249

Low

918338

RL26B
Large ribosomal subunit protein uL24B

1

0

High-throughput

0.249

Low

1052542

LAS17
Proline-rich protein LAS17

1

0

Small-scale

0.249

Low

810900

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.232

Low

863740

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

1035331

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025