Protein: GAL4
Regulatory protein GAL4

Gene: GAL4
Organism: Saccharomyces cerevisiae S288C
Interactions: 82
UniProt ID: P04386

Gene Ontology (top 5):
GO:0000431 - regulation of transcription from RNA polymerase II promoter by galactose
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

408372

GAL4
Regulatory protein GAL4

3

16

Small-scale

0.865

High

408373

GAL80
Galactose/lactose metabolism regulatory protein GAL80

27

1

Small-scale

0.769

High

408390

MED15
Mediator of RNA polymerase II transcription subunit 15

13

1

Small-scale

0.762

High

408415

SSN3
Meiotic mRNA stability protein kinase SSN3

6

8

Small-scale

0.738

High

408387

TBP
TATA-box-binding protein

8

0

Small-scale

0.722

High

408395

TF2B
Transcription initiation factor IIB

5

14

Small-scale

0.714

High

408432

PRS8
26S proteasome regulatory subunit 8 homolog

4

2

Small-scale

0.694

High

408397

MED17
Mediator of RNA polymerase II transcription subunit 17

5

0

Small-scale

0.691

High

408429

PRS10
26S proteasome subunit RPT4

3

2

Small-scale

0.674

High

408411

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

3

1

Small-scale

0.654

High

408433

ADA2
SAGA complex subunit ADA2

3

4

Small-scale

0.651

High

408391

SNF2
Transcription regulatory protein SNF2

3

4

Small-scale

0.647

High

408434

HAP5
Transcriptional activator HAP5

2

1

Small-scale

0.620

High

408377

SNF1
Carbon catabolite-derepressing protein kinase

2

1

Small-scale

0.595

High

408425

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

2

3

Small-scale

0.594

High

408427

TAF4
Transcription initiation factor TFIID subunit 4

2

1

Small-scale

0.594

High

408428

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

2

2

Small-scale

0.576

High

408426

MED21
Mediator of RNA polymerase II transcription subunit 21

2

0

Small-scale

0.561

High

408442

MHR1
Large ribosomal subunit protein mL67

1

0

Small-scale

0.537

High

408382

NHP6B
Non-histone chromosomal protein 6B

1

1

Small-scale

0.527

High

408259

GAL1
Galactokinase

1

1

Small-scale

0.501

High

408386

GAL3
Protein GAL3

1

1

Small-scale

0.501

High

408401

STH1
Nuclear protein STH1/NPS1

1

4

Small-scale

0.501

High

408402

PRS6A
26S proteasome regulatory subunit 6A

1

1

Small-scale

0.501

High

408403

PRS6B
26S proteasome regulatory subunit 6B homolog

1

1

Small-scale

0.501

High

408404

PRS7
26S proteasome regulatory subunit 7 homolog

1

2

Small-scale

0.501

High

408406

SPT7
SAGA complex subunit SPT7

1

6

Small-scale

0.501

High

408416

PRS4
26S proteasome regulatory subunit 4 homolog

1

2

Small-scale

0.501

High

408374

H2A1
Histone H2A.1

1

2

Small-scale

0.481

High

408378

SPT3
SAGA complex subunit SPT3

1

1

Small-scale

0.481

High

408379

RAD2
DNA repair protein RAD2

1

1

Small-scale

0.481

High

408383

TAF13
Transcription initiation factor TFIID subunit 13

1

1

Small-scale

0.481

High

408400

SWI3
SWI/SNF complex subunit SWI3

1

4

Small-scale

0.481

High

408408

CCL1
Cyclin CCL1

1

2

Small-scale

0.481

High

408436

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

2

Small-scale

0.481

High

408440

TAF7
Transcription initiation factor TFIID subunit 7

1

1

Small-scale

0.481

High

408446

TAF10
SAGA complex/transcription factor TFIID complex subunit TAF10

1

1

Small-scale

0.481

High

408394

INO2
Protein INO2

1

0

Small-scale

0.480

High

408410

MED6
Mediator of RNA polymerase II transcription subunit 6

1

0

Small-scale

0.480

High

408421

EPL1
Enhancer of polycomb-like protein 1

1

0

Small-scale

0.480

High

408424

EAF6
Chromatin modification-related protein EAF6

1

0

Small-scale

0.480

High

408431

SNF12
Transcription regulatory protein SNF12

1

0

Small-scale

0.480

High

408376

RS3
Small ribosomal subunit protein uS3

1

2

Small-scale

0.479

High

408380

YD14B
Transposon Ty1-DR5 Gag-Pol polyprotein

1

2

Small-scale

0.479

High

408388

CYPH
Peptidyl-prolyl cis-trans isomerase

1

1

Small-scale

0.479

High

408392

MAS5
Mitochondrial protein import protein MAS5

1

8

Small-scale

0.479

High

408396

XPO1
Exportin-1

1

1

Small-scale

0.479

High

408407

BDF1
Bromodomain-containing factor 1

1

4

Small-scale

0.479

High

408417

MED3
Mediator of RNA polymerase II transcription subunit 3

1

1

Small-scale

0.479

High

408437

YD11B
Transposon Ty1-DR1 Gag-Pol polyprotein

1

2

Small-scale

0.479

High

408439

GAL83
SNF1 protein kinase subunit beta-3

1

1

Small-scale

0.479

High

408449

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

Small-scale

0.479

High

408384

RAP1
DNA-binding protein RAP1

1

0

Small-scale

0.460

High

408393

SRB8
Mediator of RNA polymerase II transcription subunit 12

1

0

Small-scale

0.460

High

408412

RPB11
DNA-directed RNA polymerase II subunit RPB11

1

0

Small-scale

0.460

High

408413

SNF11
Transcription regulatory protein SNF11

1

0

Small-scale

0.460

High

408418

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

Small-scale

0.460

High

408430

H1
Histone H1

1

0

Small-scale

0.460

High

408438

TAF11
Transcription initiation factor TFIID subunit 11

1

0

Small-scale

0.460

High

408444

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

Small-scale

0.460

High

408445

TFB4
General transcription and DNA repair factor IIH subunit TFB4

1

0

Small-scale

0.460

High

408450

AHC1
Protein AHC1

1

0

Small-scale

0.460

High

403284

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

Small-scale

0.458

High

408398

MED22
Mediator of RNA polymerase II transcription subunit 22

1

0

Small-scale

0.458

High

408399

MED18
Mediator of RNA polymerase II transcription subunit 18

1

0

Small-scale

0.458

High

408405

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

Small-scale

0.458

High

408420

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

0

Small-scale

0.458

High

408422

BLM10
Proteasome activator BLM10

1

0

Small-scale

0.458

High

408385

SIR4
Regulatory protein SIR4

1

1

Small-scale

0.439

High

408375

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

1

Small-scale

0.437

High

408381

IF4A
ATP-dependent RNA helicase eIF4A

1

2

Small-scale

0.437

High

408389

STI1
Heat shock protein STI1

1

1

Small-scale

0.437

High

408435

NOG1
Nucleolar GTP-binding protein 1

1

1

Small-scale

0.437

High

408441

RRP5
rRNA biogenesis protein RRP5

1

1

Small-scale

0.437

High

408447

SGT2
Small glutamine-rich tetratricopeptide repeat-containing protein 2

1

1

Small-scale

0.437

High

408448

BAG7
Rho-GTPase-activating protein BAG7

1

1

Small-scale

0.437

High

408419

6P21
6-phosphofructo-2-kinase 1

1

1

High-throughput

0.407

High

408409

AHP1
Peroxiredoxin AHP1

1

0

Small-scale

0.249

Low

408414

HXT6
High-affinity hexose transporter HXT6

1

0

Small-scale

0.249

Low

408423

TCPQ
T-complex protein 1 subunit theta

1

0

Small-scale

0.249

Low

408443

YSP2
Membrane-anchored lipid-binding protein YSP2

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025