Interactor 1: MCM7 (P33993)
DNA replication licensing factor MCM7 (EC 3.6.4.12) (CDC47 homolog) (P1.1-MCM3)
Gene: MCM7

Interactor 2: PSF2 (Q9Y248)
DNA replication complex GINS protein PSF2 (GINS complex subunit 2)
Gene: GINS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~Sld5, MCM_N~Sld5
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006268 - DNA unwinding involved in DNA replication
GO:0071162 - CMG complex
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 719
Hs

1 185
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Sp
+ Sc
+ Sc
+ Sc
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024