HitPredict

Interactor 1: VPS35 (P34110)
Vacuolar protein sorting-associated protein 35 (Vacuolar protein-targeting protein 7)
Gene: VPS35

Interactor 2: VPS35 (P34110)
Vacuolar protein sorting-associated protein 35 (Vacuolar protein-targeting protein 7)
Gene: VPS35

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	1.00	0.854

The method score is based on:

Property	Details
Experiments	18467557, 36644906, 22940862
Identification Methods	protein complementation assay, pull down, affinity chromatography technology, dihydrofolate reductase reconstruction
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Vps35~Vps35
Common GO terms	GO:0000329 - fungal-type vacuole membrane GO:0005768 - endosome GO:0005770 - late endosome GO:0005829 - cytosol GO:0006886 - intracellular protein transport and 7 others more... GO:0012505 - endomembrane system GO:0030904 - retromer complex GO:0030906 - retromer, cargo-selective complex GO:0032456 - endocytic recycling GO:0042147 - retrograde transport, endosome to Golgi GO:0045053 - protein retention in Golgi apparatus GO:1900102 - negative regulation of endoplasmic reticulum unfolded protein response
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	944
Sc

1	944

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024