HitPredict

Interactor 1: MXI1 (P50539)
Max-interacting protein 1 (Max interactor 1) (Class C basic helix-loop-helix protein 11) (bHLHc11)
Gene: MXI1

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	29507620, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0046983 - protein dimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 228 Hs			1 605
+	Hs
		840227 MXI1_HUMAN (1-228): 1.73e-90: 267: 100.00		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		348277 MYC_HUMAN (27-150): 5.94e-37: 136: 28.03		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		585679 TFE3_HUMAN (35-183): 3.66e-09: 57.9: 18.47		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		898218 MAX_HUMAN (60-166): 6.51e-12: 63.3: 19.63		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		585677 TFE3_HUMAN (35-183): 3.66e-09: 57.9: 18.47		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Mm
		348444 MYC_MOUSE (27-150): 2.88e-37: 136: 28.03		FBXW7_MOUSE (76-527): 2.98e-83: 277: 23.71
+	Hs
		347517 MYC_HUMAN (27-150): 5.94e-37: 136: 28.03		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		379688 MYCN_HUMAN (26-148): 3.93e-34: 128: 23.70		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		346159 MYC_HUMAN (27-150): 5.94e-37: 136: 28.03		LIS1_HUMAN (174-494): 8.99e-74: 243: 21.37
+	Hs
		898168 MAX_HUMAN (60-166): 6.51e-12: 63.3: 19.63		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		348035 MYC_HUMAN (27-150): 5.94e-37: 136: 28.03		NLE1_HUMAN (33-408): 1.35e-41: 159: 13.21
+	Dm
		1375911 MYC_DROME (64-153): 1.73e-21: 94.1: 24.47		FBXW7_DROME (414-604): 1.53e-53: 199: 30.73
+	Hs
		209372 MYC_HUMAN (27-150): 5.94e-37: 136: 28.03		PLRG1_HUMAN (417-604): 2.83e-38: 150: 23.47
+	Hs
		346404 MYC_HUMAN (27-150): 5.94e-37: 136: 28.03		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		209375 MYCN_HUMAN (26-148): 3.93e-34: 128: 23.70		PLRG1_HUMAN (417-604): 2.83e-38: 150: 23.47
+	Hs
		196936 MYC_HUMAN (27-150): 5.94e-37: 136: 28.03		PRP4_HUMAN (387-594): 6.19e-35: 140: 23.66
+	Hs
		379200 MYCN_HUMAN (26-148): 3.93e-34: 128: 23.70		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		607803 USF1_HUMAN (39-162): 5.04e-33: 123: 22.31		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Mm
		659344 MAX_MOUSE (60-166): 2.79e-12: 64.5: 19.63		WDR5_MOUSE (458-605): 5.01e-38: 145: 25.33
+	Hs
		898091 MAX_HUMAN (60-166): 6.51e-12: 63.3: 19.63		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33