HitPredict

Interactor 1: YKA7 (P34258)
Uncharacterized protein B0303.7
Gene: B0303.7

Interactor 2: DYN1 (P39055)
Dynamin (EC 3.6.5.5)
Gene: dyn-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.80	0.729

Property	Details
Experiments	19123269, 23549480
Identification Methods	two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PH~SH3_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 493 Ce			1 830
+	Mm
		760469 ITSN1_MOUSE (3-357): 1.55e-30: 128: 15.51		DYN1_MOUSE (5-826): 0: 995: 62.05
+	Hs
		557664 NCK1_HUMAN (130-350): 6.22e-31: 125: 17.83		DYN1_HUMAN (5-820): 0: 996: 62.07
+	Rn
		599413 ITSN1_RAT (3-357): 1.14e-30: 128: 15.51		DYN1_RAT (5-820): 0: 991: 62.31
+	Mm
		223006 NCK2_MOUSE (126-360): 4.5e-30: 122: 16.80		DYN1_MOUSE (5-826): 0: 995: 62.05
+	Hs
		209034 NCK2_HUMAN (126-351): 3.85e-29: 120: 18.72		DYN1_HUMAN (5-820): 0: 996: 62.07
+	Mm
		760488 ITSN1_MOUSE (3-357): 1.55e-30: 128: 15.51		DYN2_MOUSE (5-830): 0: 986: 63.59
+	Ce
		760510 Q9U2T9_CAEEL (30-493): 7.29e-30: 126: 14.76		DYN1_CAEEL (1-762): 0: 986: 100.00
+	Hs
		983379 ITSN1_HUMAN (27-493): 1.28e-20: 98: 14.14		DYN1_HUMAN (5-820): 0: 996: 62.07
+	Hs
		840840 ITSN2_HUMAN (185-437): 5.28e-24: 108: 18.22		DYN2_HUMAN (5-830): 0: 982: 63.05
+	Hs
		840719 SH319_HUMAN (176-413): 5.3e-22: 101: 19.60		DYN2_HUMAN (5-830): 0: 982: 63.05
+	Ce
		666206 SEM5_CAEEL (255-335): 3.44e-21: 94.2: 25.93		DYN1_CAEEL (1-762): 0: 986: 100.00
+	Hs
		840702 ITSN1_HUMAN (27-493): 1.28e-20: 98: 14.14		DYN2_HUMAN (5-830): 0: 982: 63.05
+	Hs
		983399 SH3K1_HUMAN (360-493): 5.24e-14: 76.5: 18.47		DYN1_HUMAN (5-820): 0: 996: 62.07
+	Mm
		760462 SH3K1_MOUSE (360-493): 8.89e-14: 76.1: 19.11		DYN1_MOUSE (5-826): 0: 995: 62.05
+	Mm
		760481 SH3K1_MOUSE (360-493): 8.89e-14: 76.1: 19.11		DYN2_MOUSE (5-830): 0: 986: 63.59
+	Rn
		192739 SRBS2_RAT (342-492): 8.16e-12: 69.9: 21.85		DYN1_RAT (5-820): 0: 991: 62.31
+	Hs
		840686 GRAP_HUMAN (197-413): 5.81e-16: 78.8: 16.29		DYN2_HUMAN (5-830): 0: 982: 63.05
+	Hs
		840786 SH3K1_HUMAN (360-493): 5.24e-14: 76.5: 18.47		DYN2_HUMAN (5-830): 0: 982: 63.05
+	Rn
		192740 SRBS2_RAT (342-492): 8.16e-12: 69.9: 21.85		DYN2_RAT (5-830): 0: 985: 63.59
+	Dm
		649302 GRAP_DROME (255-330): 9.06e-20: 89.6: 30.26		DYN_DROME (8-830): 0: 949: 65.58