HitPredict

Interactor 1: BRE1 (P34537)
E3 ubiquitin-protein ligase bre-1 (EC 2.3.2.27) (RING finger protein rfp-1) (RING-type E3 ubiquitin transferase bre-1)
Gene: rfp-1

Interactor 2: UBC1 (P52478)
Ubiquitin-conjugating enzyme E2 1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 1) (Ubiquitin carrier protein 1) (Ubiquitin-protein ligase 1)
Gene: ubc-1

Species: Caenorhabditis elegans

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.953

The method score is based on:

Property Details
Experiments 19123269, 15530417, 12679813, 14732404, 14704431, 11778048
Identification Methods two hybrid, pull down, two hybrid array, two hybrid pooling approach, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~zf-C3HC4
Common GO terms GO:0016567 - protein ubiquitination
GO:0033503 - HULC complex
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 837
Ce

1 192
+ Ce
+ At
+ At
+ Sc
+ Hs
+ Hs
+ Sp
+ Hs
+ Hs
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024